Image-based profiling is a maturing strategy by which the rich information present in
biological images is reduced to a multidimensional profile, a collection of extracted image …

This chapter outlines some general issues in searching for studies; describes the main
sources of potential studies; and discusses how to plan the search process, design and …

Over the past decade, artificial intelligence (AI) and machine learning (ML) have become the
breakthrough technology most anticipated to have a transformative effect on pharmaceutical …

Clinical trials are time consuming, expensive, and often burdensome on patients. Clinical
trials can fail for many reasons. This survey reviews many of these reasons and offers …

Background Repurposing is a drug development strategy receiving heightened attention
after the Food and Drug Administration granted emergency use authorization of several …

This article provides a brief overview of the processes of drug discovery and development.
Our aim is to help scientists whose research may be relevant to drug discovery and/or …

In the past decade, the emergence of machine learning (ML) applications has led to
significant advances towards implementation of personalised medicine approaches for …

Sažetak Studies with positive results are greatly more represented in literature than studies
with negative results, producing so-called publication bias. This review aims to discuss …

Background The pharmaceutical industry is in the midst of a productivity crisis and rates of
translation from bench to bedside are dismal. Patients are being let down by the current …

The first microfluidic microphysiological systems (MPS) entered the academic scene more
than 15 years ago and were considered an enabling technology to human in vitro (patho) …