Noncoding RNA therapeutics—challenges and potential solutions

M Winkle, SM El-Daly, M Fabbri, GA Calin - Nature reviews Drug …, 2021 - nature.com
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …

Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain

AJ McFarland, MS Yousuf, S Shiers, TJ Price - Pain reports, 2021 - journals.lww.com
SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …

Single-cell transcriptome analysis highlights a role for neutrophils and inflammatory macrophages in the pathogenesis of severe COVID-19

H Shaath, R Vishnubalaji, E Elkord, NM Alajez - Cells, 2020 - mdpi.com
Cumulative data link cytokine storms with coronavirus disease 2019 (COVID-19) severity.
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …

[HTML][HTML] Epigenome-wide association study of COVID-19 severity with respiratory failure

MC de Moura, V Davalos, L Planas-Serra… - …, 2021 - thelancet.com
Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …

The regulation of lncRNAs and miRNAs in SARS-CoV-2 infection

Y Lin, Q Sun, B Zhang, W Zhao, C Shen - Frontiers in Cell and …, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) was a global endemic that continues to cause a
large number of severe illnesses and fatalities. There is increasing evidence that non-coding …

Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

X Liu, W Xiong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …

The expression patterns of MALAT-1, NEAT-1, THRIL, and miR-155-5p in the acute to the post-acute phase of COVID-19 disease

M Abbasi-Kolli, JS Nahand, SJ Kiani… - Brazilian Journal of …, 2022 - SciELO Brasil
Introduction: One of the hallmarks of COVID-19 is overwhelming inflammation, which plays a
very important role in the pathogenesis of COVID-19. Thus, identification of inflammatory …

The emerging roles of IFIT3 in antiviral innate immunity and cellular biology

W Zhang, Y Li, S Xin, L Yang, M Jiang… - Journal of medical …, 2023 - Wiley Online Library
The interferon‐inducible protein with tetrapeptide repeats 3 (IFIT3) is one of the most
important members in both the IFIT family and interferon‐stimulated genes family. IFIT3 has …

Interplay between SARS‐CoV‐2 and human long non‐coding RNAs

M Moazzam‐Jazi, H Lanjanian… - Journal of cellular …, 2021 - Wiley Online Library
The long non‐coding RNAs (lncRNAs) play a critical regulatory role in the host response to
the viral infection. However, little is understood about the transcriptome architecture …

Long noncoding RNAs as emerging regulators of COVID-19

Q Yang, F Lin, Y Wang, M Zeng, M Luo - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), which has high incidence rates with rapid rate of
transmission, is a pandemic that spread across the world, resulting in more than 3,000,000 …