Cuproptosis: Harnessing transition metal for cancer therapy

W Wang, W Mo, Z Hang, Y Huang, H Yi, Z Sun, A Lei - ACS nano, 2023 - ACS Publications
Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …

Biomarker‐responsive nanosystems for chronic disease theranostics

Q Fu, L Yu, Y Wang, P Li, J Song - Advanced Functional …, 2023 - Wiley Online Library
Chronic diseases claim millions of lives every year, and it is of great significance to explore
and develop advanced drugs to improve the cure rate of chronic diseases. Nanotheranostics …

Extracellular Cu2+ pools and their detection: From current knowledge to next-generation probes

E Falcone, M Okafor, N Vitale, L Raibaut, A Sour… - Coordination Chemistry …, 2021 - Elsevier
Copper (Cu) is an essential micronutrient for most organisms and serves mainly as a redox-
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …

Activity-based sensing with a metal-directed acyl imidazole strategy reveals cell type-dependent pools of labile brain copper

S Lee, CYS Chung, P Liu, L Craciun… - Journal of the …, 2020 - ACS Publications
Copper is a required nutrient for life and particularly important to the brain and central
nervous system. Indeed, copper redox activity is essential to maintaining normal …

Multiple target detection and binding properties of naphthalene-derived Schiff-base chemosensor

S Gurusamy, K Krishnaveni, M Sankarganesh… - Journal of Molecular …, 2021 - Elsevier
A novel naphthalene-based Schiff-base ligand (NNP) was synthesized by the condensation
reaction of 2-hydroxy naphthaldehyde and N-phenyl-o-phenylenediamine in a single step …

Activatable Probes for Ratiometric Imaging of Endogenous Biomarkers In Vivo

Q Fu, X Yang, M Wang, K Zhu, Y Wang, J Song - ACS nano, 2024 - ACS Publications
Dynamic variations in the concentration and abnormal distribution of endogenous
biomarkers are strongly associated with multiple physiological and pathological states …

Responsive gadolinium (III) complex-based small molecule magnetic resonance imaging probes: Design, mechanism and application

Q Meng, M Wu, Z Shang, Z Zhang, R Zhang - Coordination Chemistry …, 2022 - Elsevier
Magnetic resonance imaging (MRI) is a molecular imaging technology that has been widely
adopted in biomedical and clinical diagnostics fields owing to its capability of deep tissue …

Chemical Amplification-Enabled Topological Modification of Nucleic Acid Aptamers for Enhanced Cancer-Targeted Theranostics

H Chen, Y Li, Z Xiao, J Li, T Li, Z Wang, Y Liu, W Tan - ACS nano, 2023 - ACS Publications
Site-specific chemical conjugation has long been a challenging endeavor in the field of
ligand-directed modification to produce homogeneous conjugates for precision medicine …

A novel colorimetric, selective fluorescent “turn-off” chemosensor and biomolecules binding studies based on iodosalicylimine schiff-base derivative

S Gurusamy, M Sankarganesh, V Sathish… - … of Photochemistry and …, 2022 - Elsevier
We have designed a new iodosalicylimine-derived Schiff-base chemosensor ISNP, which is
synthesized by the condensation reaction of 3, 5-diiodosalicylaldehyde with N-phenyl-o …

Stimulus-responsive inorganic semiconductor nanomaterials for tumor-specific theranostics

X Hu, E Ha, F Ai, X Huang, L Yan, S He, S Ruan… - Coordination Chemistry …, 2022 - Elsevier
Nanotheranostics utilizing nanoparticles for diagnostics and treatment simultaneously, have
attracted tremendous attention in anticancer therapy due to its excellent performance, such …