Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues

P D'Acunzo, Y Kim, JM Ungania, R Pérez-González… - Nature …, 2022 - nature.com
Extracellular vesicles (EVs) are nanoscale vesicles secreted into the extracellular space by
all cell types, including neurons and astrocytes in the brain. EVs play pivotal roles in …

Phagocytosis of necrotic debris at sites of injury and inflammation

J Westman, S Grinstein, PE Marques - Frontiers in immunology, 2020 - frontiersin.org
Clearance of cellular debris is required to maintain the homeostasis of multicellular
organisms. It is intrinsic to processes such as tissue growth and remodeling, regeneration …

Lamin B1 loss is a senescence-associated biomarker

A Freund, RM Laberge, M Demaria… - Molecular biology of the …, 2012 - Am Soc Cell Biol
Cellular senescence is a potent tumor-suppressive mechanism that arrests cell proliferation
and has been linked to aging. However, studies of senescence have been impeded by the …

The biochemistry of apoptosis

MO Hengartner - Nature, 2000 - nature.com
Apoptosis—the regulated destruction of a cell—is a complicated process. The decision to
die cannot be taken lightly, and the activity of many genes influence a cell's likelihood of …

Apoptosis: controlled demolition at the cellular level

RC Taylor, SP Cullen, SJ Martin - Nature reviews Molecular cell biology, 2008 - nature.com
Apoptosis is characterized by a series of dramatic perturbations to the cellular architecture
that contribute not only to cell death, but also prepare cells for removal by phagocytes and …

Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

SL Fink, BT Cookson - Infection and immunity, 2005 - Am Soc Microbiol
A wide variety of pathogenic microorganisms have been demonstrated to cause eukaryotic
cell death, either as a consequence of infecting host cells or by producing toxic products …

Improvement of the Cu and Cd phytostabilization efficiency of perennial ryegrass through the inoculation of three metal-resistant PGPR strains

T Ke, G Guo, J Liu, C Zhang, Y Tao, P Wang, Y Xu… - Environmental …, 2021 - Elsevier
To explore a novel strategy for the remediation of soils polluted with Cu and Cd, three strains
of plant-growth-promoting rhizobacteria (PGPRs) isolated from contaminated mines and two …

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

WC Earnshaw, LM Martins… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Apoptosis is a genetically programmed, morphologically distinct form of cell death
that can be triggered by a variety of physiological and pathological stimuli. Studies …

Overview of cell death signaling pathways

Z Jin, WS El-Deiry - Cancer biology & therapy, 2005 - Taylor & Francis
Apoptosis plays an important role in development and maintenance of tissue homeostasis.
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …

The lamin protein family

TA Dittmer, T Misteli - Genome biology, 2011 - Springer
The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the
inside of the nuclear membrane, where they provide a platform for the binding of proteins …