BACKGROUND Chemotherapy-associated ovarian damage (CAOD) is one of the most
feared short-and long-term side effects of anticancer treatment in premenopausal women …

Polycystic ovary syndrome (PCOS) is a disease with endocrine and metabolic disorders.
The main symptoms are hyperandrogenemia (HA), insulin resistance (IR), and ovulation …

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease, which
leads to serious impairment of reproductive health in women of child-bearing age …

Background Cyp19a1a is a key enzyme in the pathway that converts androgens into
estrogen and is regulated by TGF-β signaling. Smad4 and FoxH1 are downstream effectors …

Background Diabetic kidney disease (DKD) is a major complication of diabetes and the
leading cause of end-stage renal disease worldwide. Renal inflammation and infiltration of …

Cisplatin can lead to infertility due to its negative impact on the uterus and ovaries. This
study aimed to explore the effects of Inositol and vitamin C on cisplatin-induced infertility …

Cholesterol is a precursor to steroid hormones and can be obtained from serum LDL or de
novo synthesis in steroidogenic cells. Before luteinizing hormone (LH) surge-induced …

Ovarian hyperstimulation syndrome (OHSS) is a life-threatening and potentially fatal
complication during in vitro fertilization treatment. The levels of transforming growth factor-β1 …

5-Hydroxytryptamine (5-HT) is an inhibitory neurotransmitter widely distributed in
mammalian tissues, exerting its effects through binding to various receptors. It plays a crucial …

Background Ovarian hyperstimulation syndrome (OHSS) is a serious complication during in
vitro fertilization (IVF) treatment. The upregulation of ovarian transforming growth factor-beta …