Illuminating the oral microbiome and its host interactions: animal models of disease

G Hajishengallis - FEMS Microbiology Reviews, 2023 - academic.oup.com
Periodontitis and caries are driven by complex interactions between the oral microbiome
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …

Social networking at the microbiome-host interface

RJ Lamont, G Hajishengallis, H Koo - Infection and Immunity, 2023 - Am Soc Microbiol
Microbial species colonizing host ecosystems in health or disease rarely do so alone.
Organisms conglomerate into dynamic heterotypic communities or biofilms in which …

A host-adapted auxotrophic gut symbiont induces mucosal immunodeficiency

Q Lu, TCA Hitch, JY Zhou, M Dwidar, N Sangwan… - Science, 2024 - science.org
Harnessing the microbiome to benefit human health requires an initial step in determining
the identity and function of causative microorganisms that affect specific host physiological …

Antimicrobial peptides: Defending the mucosal epithelial barrier

KF Johnstone, MC Herzberg - Frontiers in Oral Health, 2022 - frontiersin.org
The recent epidemic caused by aerosolized SARS-CoV-2 virus illustrates the importance
and vulnerability of the mucosal epithelial barrier against infection. Antimicrobial proteins …

Bacterial multispecies interaction mechanisms dictate biogeographic arrangement between the oral commensals Corynebacterium matruchotii and Streptococcus …

E Almeida, S Puri, A Labossiere, S Elangovan, J Kim… - Msystems, 2023 - Am Soc Microbiol
Polymicrobial biofilms are present in many environments particularly in the human oral
cavity where they can prevent or facilitate the onset of disease. While recent advances have …

Etiopathogenesis of Psoriasis: Integration of Proposed Theories

BF Hernandez-Nicols, JJ Robledo-Pulido… - Immunological …, 2024 - Taylor & Francis
Psoriasis is a chronic inflammatory disease characterized by squamous and erythematous
plaques on the skin and the involvement of the immune system. Global prevalence for …

Mechanistic assessment of metabolic interaction between single oral commensal cells by scanning electrochemical microscopy

SR Puri, E Almeida, S Elangovan… - Analytical …, 2023 - ACS Publications
The human oral microbiome heavily influences the status of oral and systemic diseases
through different microbial compositions and complex signaling between microbes. Recent …

Phages are unrecognized players in the ecology of the oral pathogen Porphyromonas gingivalis

CB Matrishin, EM Haase, FE Dewhirst, JL Mark Welch… - Microbiome, 2023 - Springer
Abstract Background Porphyromonas gingivalis (hereafter “Pg”) is an oral pathogen that has
been hypothesized to act as a keystone driver of inflammation and periodontal disease …

Illuminating the oral microbiome and its host interactions: tools and approaches for molecular ecological studies

J Kreth, J Merritt - FEMS Microbiology Reviews, 2023 - academic.oup.com
A more comprehensive understanding of oral diseases like caries and periodontitis is
dependent on an intimate understanding of the microbial ecological processes that are …

Human saliva modifies growth, biofilm architecture, and competitive behaviors of oral streptococci

A Choi, K Dong, E Williams, L Pia, J Batagower… - Msphere, 2024 - Am Soc Microbiol
The bacteria within supragingival biofilms participate in complex exchanges with other
microbes inhabiting the same niche. One example is the mutans group streptococci …