Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
[HTML][HTML] MicroRNAs in autoimmune thyroid diseases and their role as biomarkers
R Martínez-Hernández, M Marazuela - Best Practice & Research Clinical …, 2023 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the
posttranscriptional level. They are emerging as potential biomarkers and as therapeutic …
posttranscriptional level. They are emerging as potential biomarkers and as therapeutic …
The role of thyroid hormone in the renal immune microenvironment
Z Han, L Chen, H Peng, H Zheng, Y Lin, F Peng… - International …, 2023 - Elsevier
Thyroid hormones are essential for proper kidney growth and development. The kidney is
not only the organ of thyroid hormone metabolism but also the target organ of thyroid …
not only the organ of thyroid hormone metabolism but also the target organ of thyroid …
Decreased expression of miR-29 family associated with autoimmune myasthenia gravis
MA Cron, CA Payet, OM Fayet, S Maillard… - Journal of …, 2020 - Springer
Background Myasthenia gravis (MG) is a rare autoimmune disease mainly mediated by
autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction …
autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction …
Emerging roles for noncoding RNAs in autoimmune thyroid disease
L Yin, C Zeng, J Yao, J Shen - Endocrinology, 2020 - academic.oup.com
Autoimmune thyroid disease (AITD) is one of the most frequent autoimmune disorders.
However, the pathogenesis of AITD has not been fully elucidated. Recently, accumulating …
However, the pathogenesis of AITD has not been fully elucidated. Recently, accumulating …
DNA hypermethylation of PTPN22 gene promoter in children and adolescents with Hashimoto thyroiditis
I Kyrgios, S Giza, A Fragou, G Tzimagiorgis… - Journal of …, 2021 - Springer
Purpose Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is an inhibitor of T-
cell activation, regulating intracellular signal transduction and thereby being implicated in …
cell activation, regulating intracellular signal transduction and thereby being implicated in …
Nonspecific Orbital Inflammation (NSOI): Unraveling the Molecular Pathogenesis, Diagnostic Modalities, and Therapeutic Interventions
KY Wu, M Kulbay, P Daigle, BH Nguyen… - International Journal of …, 2024 - mdpi.com
Nonspecific orbital inflammation (NSOI), colloquially known as orbital pseudotumor,
sometimes presents a diagnostic and therapeutic challenge in ophthalmology. This review …
sometimes presents a diagnostic and therapeutic challenge in ophthalmology. This review …
A systematic review of dysregulated microRNAs in Hashimoto's thyroiditis
Background Plenty of evidence suggests that dysregulated microRNAs are linked to
developing autoimmune thyroid diseases. In this study, we aimed to identify commonly …
developing autoimmune thyroid diseases. In this study, we aimed to identify commonly …
Identification of miR-29a as a novel biomarker for lumpy skin disease virus exposure in cattle
Micro RNAs (miRNAs) have been implicated in the regulation of maturation, proliferation,
differentiation, and activation of immune cells. In this study, we demonstrated that miR-29a …
differentiation, and activation of immune cells. In this study, we demonstrated that miR-29a …
HDAC6-specific inhibitor alleviates hashimoto's thyroiditis through inhibition of Th17 cell differentiation
Q Chang, D Yin, H Li, X Du, Z Wang, Y Liu… - Molecular Immunology, 2022 - Elsevier
Objective Hashimoto's thyroiditis (HT) is one of the commonest autoimmune disorders. This
study was performed to investigate the potential effect of histone deacetylase 6-specific …
study was performed to investigate the potential effect of histone deacetylase 6-specific …