Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Glycosylated natural products and synthetic glycopeptides represent a significant and
growing source of biochemical probes and therapeutic agents. However, methods that …

Glycosylation is one of the most prevalent post-translational modifications of a protein, with a
defining impact on its structure and function. Many of the proteins involved in the innate or …

A wide variety of antimicrobial peptides produced by lactic acid bacteria (LAB) have been
identified and studied in the last decades. Known as bacteriocins, these ribosomally …

Highlights•Glycocins fall into two mechanistic classes: bactericidal and bacteriostatic.•There
are four types of disulfide-bonded glycocins based on aa sequences and PTMs.•Genomic …

Peptide and protein aberrant lipidation patterns are often involved in many diseases
including cancer and neurological disorders. Peptide lipidation is also a promising strategy …

The COVID-19 pandemic caused by novel SARS-CoV-2 has resulted in an unprecedented
loss of lives and economy around the world. In this study, search for potential inhibitors …

Glycocin F (GccF) is a unique diglycosylated bacteriocin peptide that possesses potent and
reversible bacteriostatic activity against a range of Gram-positive bacteria. GccF is a rare …

Consumer demand for natural or'clean-label'food ingredients has risen over the past 50
years and continues growing. Consumers have become more aware of their health and …