Acrylamide in bakery products: A review on health risks, legal regulations and strategies to reduce its formation

C Sarion, GG Codină, A Dabija - International Journal of Environmental …, 2021 - mdpi.com
Acrylamide is a contaminant as defined in Council Regulation (EEC) No 315/93 and as
such, it is considered a chemical hazard in the food chain. The toxicity of acrylamide has …

Recent Strategies and Applications for l-Asparaginase Confinement

JCF Nunes, RO Cristóvão, MG Freire… - Molecules, 2020 - mdpi.com
l-asparaginase (ASNase, EC 3.5. 1.1) is an aminohydrolase enzyme with important uses in
the therapeutic/pharmaceutical and food industries. Its main applications are as an …

Effective mitigation in the amount of acrylamide through enzymatic approaches

E Abedi, SMB Hashemi, F Ghiasi - Food Research International, 2023 - Elsevier
Acrylamide (AA), as a food-borne toxicant, is created at some stages of thermal processing
in the starchy food through Maillard reaction, fatty food via acrolein route, and proteinous …

Strain improvement, artificial intelligence optimization, and sensitivity analysis of asparaginase-mediated acrylamide reduction in sweet potato chips

E Akwagiobe, M Ekpenyong, A Asitok… - Journal of Food Science …, 2023 - Springer
In recent times, L-asparaginase has emerged as a potential anti-carcinogen through
hydrolysis of L-asparagine in the blood for anti-leukemic application, and in carbohydrate …

Bioprospecting of the agaricomycete Ganoderma australe GPC191 as novel source for l-asparaginase production

M Chakraborty, S Shivakumar - Scientific Reports, 2021 - nature.com
Abstract l-Asparaginase is a therapeutically and industrially-competent enzyme, acting
predominantly as an anti-neoplastic and anti-cancerous agent. The existing formulations of …

Immobilization of recombinant L-asparaginase from Geobacillus kaustophilus on magnetic MWCNT-nickel composites

Fİ Özdemir, B Karaaslan, A Tülek, G Yucebilgic… - Process …, 2023 - Elsevier
In this study, L-asparaginase from thermophilic Geobacillus kaustophilus was
heterologously expressed in Escherichia coli and purified by 6.14-fold using Ni-NTA column …

Investigation of composition, temperature, and heating time in the formation of acrylamide in snack: central composite design optimization and microextraction coupled …

M Kamankesh, A Nematollahi, A Mohammadi… - Food Analytical …, 2021 - Springer
Snack samples like potato crisp, fried potato, popcorn, and Cheetos have been known as
carbohydrate-and protein-rich food. These tasty foods have high potential to contain …

Evaluation of the efficiency of thermostable l-asparaginase from B. licheniformis UDS-5 for acrylamide mitigation during preparation of French fries

D Joshi, H Patel, S Suthar, DH Patel… - World Journal of …, 2024 - Springer
A thermostable l-asparaginase was produced from Bacillus licheniformis UDS-5 (GenBank
accession number, OP117154). The production conditions were optimized by the Plackett …

Formation and identification of six amino acid-acrylamide adducts and their cytotoxicity toward gastrointestinal cell lines

D Li, F Xian, J Ou, K Jiang, J Zheng, S Ou, F Liu… - Frontiers in …, 2022 - frontiersin.org
Acrylamide (AA) is a food contaminant, and amino acids are suggested to mitigate its toxicity
by forming adducts. The emergence of acrylamide adducts may cause underestimation of …

Anticancer L-Asparaginase and Phytoactive Compounds From Plant Solanum nigrum Against MDR (Methicillindrug resistant) Staphylococcus aureus and Fungal …

A Aisha, S Zahra, IM Tahir, A Hussain… - Dose …, 2022 - journals.sagepub.com
L-asparaginase is used in chemotherapy for acute lymphoblastic leukemia and other
cancers. L-asparaginase derived from bacterial source triggers immune responses. The …