Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

The therapeutic potential of curcumin: A review of clinical trials

B Salehi, Z Stojanović-Radić, J Matejić… - European journal of …, 2019 - Elsevier
Curcuma longa L., its derived extracts and even its major compound curcumin has a long
history of use and doubtless effectiveness, reported through increasingly detailed in vitro, ex …

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Therapeutic roles of curcumin: lessons learned from clinical trials

SC Gupta, S Patchva, BB Aggarwal - The AAPS journal, 2013 - Springer
Extensive research over the past half century has shown that curcumin (diferuloylmethane),
a component of the golden spice turmeric (Curcuma longa), can modulate multiple cell …

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Arsenic: toxicity, oxidative stress and human disease

K Jomova, Z Jenisova, M Feszterova… - Journal of applied …, 2011 - Wiley Online Library
Arsenic (As) is a toxic metalloid element that is present in air, water and soil. Inorganic
arsenic tends to be more toxic than organic arsenic. Examples of methylated organic …

Arsenic-induced oxidative stress and its reversibility

SJS Flora - Free Radical Biology and Medicine, 2011 - Elsevier
This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Free radicals as a double-edged sword: The cancer preventive and therapeutic roles of curcumin

N Gupta, K Verma, S Nalla, A Kulshreshtha, R Lall… - Molecules, 2020 - mdpi.com
Free radicals, generally composed of reactive oxygen species (ROS) and reactive nitrogen
species (RNS), are generated in the body by various endogenous and exogenous systems …