Tumour-associated macrophages (TAMs) are crucial components of the tumour
microenvironment and play a significant role in tumour development and drug resistance by …

Mitochondria are critical for regulation of the activation, differentiation, and survival of
macrophages and other immune cells. In response to various extracellular signals, such as …

Lactate accumulation is a hallmark of solid cancers and is linked to the immune suppressive
phenotypes of tumor-infiltrating immune cells. We report herein that interleukin-4 (IL-4) …

Profound metabolic changes are characteristic of macrophages during classical activation
and have been implicated in this phenotype. Here we demonstrate that nitric oxide (NO) …

Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …

Recently, strategies that can target the underlying mechanisms of phenotype change to
modulate the macrophage immune response from the standpoint of biological science have …

The immune microenvironment plays a vital role in bone defect repair. To create an immune
microenvironment that promotes osteogenesis, researchers are exploring ways to enhance …

Mitochondria are essential cellular organelles that are involved in regulating cellular energy,
metabolism, survival, and proliferation. To some extent, cancer is a genetic and metabolic …

We conducted a systematic review of the literature on the effects of cordycepin on cell
survival and proliferation, inflammation, signal transduction and animal models. A total of …

Sepsis presents as a severe infectious disease frequently documented in clinical settings.
Characterized by its systemic inflammatory response syndrome, sepsis has the potential to …