Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial
Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …
biology depend on obtaining consistent and quantitatively accurate proteomics data from …
Advances in data‐independent acquisition mass spectrometry towards comprehensive digital proteome landscape
RB Kitata, JC Yang, YJ Chen - Mass spectrometry reviews, 2023 - Wiley Online Library
The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …
powerful alternative for highly reproducible proteome profiling with a unique strength of …
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are
susceptible to senescence during aging. We demonstrate the importance of the amount of …
susceptible to senescence during aging. We demonstrate the importance of the amount of …
Integrated proteogenomic characterization of human high-grade serous ovarian cancer
To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …
Multi-omic measurements of heterogeneity in HeLa cells across laboratories
Reproducibility in research can be compromised by both biological and technical variation,
but most of the focus is on removing the latter. Here we investigate the effects of biological …
but most of the focus is on removing the latter. Here we investigate the effects of biological …
Optimization of experimental parameters in data-independent mass spectrometry significantly increases depth and reproducibility of results
Comprehensive, reproducible and precise analysis of large sample cohorts is one of the key
objectives of quantitative proteomics. Here, we present an implementation of data …
objectives of quantitative proteomics. Here, we present an implementation of data …
Mass spectrometry‐based protein–protein interaction networks for the study of human diseases
AL Richards, M Eckhardt, NJ Krogan - Molecular systems biology, 2021 - embopress.org
A better understanding of the molecular mechanisms underlying disease is key for
expediting the development of novel therapeutic interventions. Disease mechanisms are …
expediting the development of novel therapeutic interventions. Disease mechanisms are …
Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
Quantitative proteomics employing mass spectrometry is an indispensable tool in life
science research. Targeted proteomics has emerged as a powerful approach for …
science research. Targeted proteomics has emerged as a powerful approach for …
Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory
M Ribeiro, HC Brigas, M Temido-Ferreira… - Science …, 2019 - science.org
The notion of “immune privilege” of the brain has been revised to accommodate its
infiltration, at steady state, by immune cells that participate in normal neurophysiology …
infiltration, at steady state, by immune cells that participate in normal neurophysiology …
[HTML][HTML] A human interactome in three quantitative dimensions organized by stoichiometries and abundances
The organization of a cell emerges from the interactions in protein networks. The
interactome is critically dependent on the strengths of interactions and the cellular …
interactome is critically dependent on the strengths of interactions and the cellular …