ENDOCRINE TUMOURS: Calcitonin in thyroid and extra-thyroid neuroendocrine neoplasms: the two-faced Janus

E Giannetta, V Guarnotta, B Altieri… - European Journal of …, 2020 - academic.oup.com
An increased calcitonin serum level is suggestive of a medullary thyroid cancer (MTC), but is
not pathognomonic. The possibility of false positives or other calcitonin-secreting …

Neuroendocrine neoplasms of lung, pancreas and gut: a morphology-based comparison

A Kasajima, G Klöppel - Endocrine-Related Cancer, 2020 - erc.bioscientifica.com
The bronchopulmonary (BP) and gastroenteropancreatic (GEP) organ systems harbor the
majority of the neuroendocrine neoplasms (NENs) of the body, comprising 20 and 70% of all …

[HTML][HTML] Endocrine abnormality in paraneoplastic syndrome

MC Onyema, EE Drakou, GK Dimitriadis - Best Practice & Research …, 2022 - Elsevier
Paraneoplastic syndromes denote rare but notable phenomena caused by the tumour
mediated release of bioactive substances. Peptide and non-peptide hormone causes are …

Severe hypercalcemia due to metastatic pancreatic neuroendocrine tumor: a case report

A Behdadnia, M Jeddi - Journal of Medical Case Reports, 2023 - Springer
Background Hypercalcemia of malignancy, as a paraneoplastic syndrome, is the most
common metabolic disorder that accounts for 30% of malignancies and usually has a poor …

Case report: unmasking hypercalcemia in patients with neuroendocrine neoplasms. Experience from six Italian referral centers

E Giannetta, F Sesti, R Modica… - Frontiers in …, 2021 - frontiersin.org
Background Hypercalcemia is a common paraneoplastic syndrome which can occur in up to
10% of patients with advanced neoplasms. Paraneoplastic parathyroid hormone-related …

Cushing's syndrome due to adrenocorticotropic hormone-secreting metastatic neuroendocrine tumor of unknown primary origin: a case report and literature review

H Bostan, H Duger, P Akhanli, M Calapkulu… - Hormones, 2022 - Springer
Background In this article, we present a case of neuroendocrine neoplasm of unknown
primary origin (UPO NEN), which is a rare cause of ectopic Cushing's syndrome (ECS) …

What lies behind paraneoplastic hypercalcemia secondary to well-differentiated neuroendocrine neoplasms? A systematic review of the literature

E Giannetta, F Sesti, R Modica… - Journal of Personalized …, 2022 - mdpi.com
Background: Neuroendocrine neoplasms (NEN) originate from neuroendocrine cells
ubiquitously spread throughout the body. Hypercalcemia associated with cancer is the most …

Calcitonin-secreting neuroendocrine neoplasms of the lung: a systematic review and narrative synthesis

DC Llewellyn, R Srirajaskanthan… - Endocrine …, 2021 - ec.bioscientifica.com
Calcitonin-secreting neuroendocrine neoplasms of the lung are rare, with few cases
reported in the literature. Differentiating between medullary thyroid carcinoma and an …

Paraneoplastic neuropathies and peripheral nerve hyperexcitability disorders

S Shelly, D Dubey, JR Mills, CJ Klein - Handbook of Clinical Neurology, 2024 - Elsevier
Peripheral neuropathy is a common referral for patients to the neurologic clinics.
Paraneoplastic neuropathies account for a small but high morbidity and mortality subgroup …

[HTML][HTML] Functioning and nonfunctioning pNENs

K Daskalakis - Current Opinion in Endocrine and Metabolic Research, 2021 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are relatively rare tumors that have been
increasingly recognized in recent years. They are highly heterogeneous and exhibit a …