More sustainable approaches for the synthesis of N-based heterocycles

NR Candeias, LC Branco, PMP Gois… - Chemical …, 2009 - ACS Publications
More Sustainable Approaches for the Synthesis of N-Based Heterocycles | Chemical Reviews
ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

Synthetic approaches to 2-arylbenzimidazoles: A review

SS Panda, R Malik, SC Jain - Current Organic Chemistry, 2012 - ingentaconnect.com
Benzimidazoles are very useful building blocks for the development of molecules that are
important in medicinal chemistry. 2-Substituted benzimidazole derivatives have found …

PEG-mediated catalyst-free expeditious synthesis of 2-substituted benzimidazoles and bis-benzimidazoles under solvent-less conditions

C Mukhopadhyay, PK Tapaswi - Tetrahedron Letters, 2008 - Elsevier
A wide variety of 2-substituted benzimidazoles and bis-benzimidazoles were synthesized in
high yields by PEG-mediated catalyst-free synthesis under solvent-less conditions. The …

Remarkable influence of substituent in ionic liquid in control of reaction: simple, efficient and hazardous organic solvent free procedure for the synthesis of 2-aryl …

D Saha, A Saha, BC Ranu - Green Chemistry, 2009 - pubs.rsc.org
A simple and efficient procedure for the synthesis of 2-substituted benzimidazoles has been
developed by a one-pot reaction of o-phenylenediamine with aromatic aldehydes in the …

[HTML][HTML] New benzimidazole-1, 2, 4-triazole hybrid compounds: Synthesis, anticandidal activity and cytotoxicity evaluation

H Karaca Gençer, U Acar Çevik, S Levent, BN Sağlık… - Molecules, 2017 - mdpi.com
Owing to the growing need for antifungal agents, we synthesized a new series 2-((5-(4-(5-
substituted-1 H-benzimidazol-2-yl) phenyl)-4-substituted-4 H-1, 2, 4-triazol-3-yl) thio)-1 …

Supercritical methanol as solvent and carbon source in the catalytic conversion of 1, 2-diaminobenzenes and 2-nitroanilines to benzimidazoles

Z Sun, G Bottari, K Barta - Green Chemistry, 2015 - pubs.rsc.org
Benzimidazoles and N-methylbenzimidazoles were synthesized by simply heating 1, 2-
diaminobenzenes in supercritical methanol over copper-doped porous metal oxides. These …

Benzimidazoles from aryl alkyl ketones and 2-amino anilines by an iodine catalyzed oxidative C (CO)–C (alkyl) bond cleavage

O Ravi, A Shaikh, A Upare, KK Singarapu… - The Journal of …, 2017 - ACS Publications
Novel molecular iodine catalyzed cyclization reactions of 2-amino anilines with aryl alkyl
ketones under oxidant and metal-free conditions are described. The reaction likely involves …

Microwave‐assisted Cadogan reaction for the synthesis of 2‐aryl‐2H‐indazoles, 2‐aryl‐1H‐benzimidazoles, 2‐carbonylindoles, carbazole, and phenazine

EC Creencia, M Kosaka, T Muramatsu… - Journal of …, 2009 - Wiley Online Library
The Cadogan reaction, a widely accepted route for the synthesis of nitrogen containing
heterocycles, is modified by using microwave radiation as the source of heat instead of the …

Insight into Microwave-Assisted Synthesis of Benzo Derivatives of Five-Membered N,N-Heterocycles

N Kaur - Synthetic Communications, 2015 - Taylor & Francis
The development of new strategies for the synthesis of small-sized heterocycles has
remained a highly attractive but challenging proposition. An overview of the application of …

A facile and efficient synthesis of benzimidazole as potential anticancer agents

TKC Huynh, THA Nguyen, NHS Tran… - Journal of Chemical …, 2020 - Springer
This study reports a simple process to synthesize and separate of 2-(substituted-phenyl)
benzimidazole derivatives with high yield and efficiency. Specifically, by reacting ortho …