Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches
M Gioia, C Ciaccio, P Calligari, G De Simone… - Biochemical …, 2020 - Elsevier
In the Fall of 2019 a sudden and dramatic outbreak of a pulmonary disease (Coronavirus
Disease COVID-19), due to a new Coronavirus strain (ie, SARS-CoV-2), emerged in the …
Disease COVID-19), due to a new Coronavirus strain (ie, SARS-CoV-2), emerged in the …
Spiking dependence of SARS‐CoV‐2 pathogenicity on TMPRSS2
AZ Abbasi, DA Kiyani, SM Hamid… - Journal of Medical …, 2021 - Wiley Online Library
Epidemiological data shows a discrepancy in COVID‐19 susceptibility and outcomes with
some regions being more heavily affected than others. However, the factors that determine …
some regions being more heavily affected than others. However, the factors that determine …
High-throughput virtual screening approach of natural compounds as target inhibitors of plasmepsin-II
Plasmepsin II is a key enzyme in the life cycle of the Plasmodium falciparum parasite
responsible for malaria, a disease that is causing deaths on a worldwide scale. Recently …
responsible for malaria, a disease that is causing deaths on a worldwide scale. Recently …
[HTML][HTML] Structural insights and inhibition mechanism of TMPRSS2 by experimentally known inhibitors Camostat mesylate, Nafamostat and Bromhexine hydrochloride …
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been
responsible for the cause of global pandemic Covid-19 and to date, there is no effective …
responsible for the cause of global pandemic Covid-19 and to date, there is no effective …
Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective
The disease caused by viral pneumonia called severe acute respiratory syndrome
coronavirus type-2 (SARS-CoV-2) declared by the World Health Organization is a global …
coronavirus type-2 (SARS-CoV-2) declared by the World Health Organization is a global …
Results of open-label non-randomized comparative clinical trial:“Bromhexine and spironolactone for coronаvirus infection requiring hospitalization (BISCUIT)
V Mareev, Y Orlova, A Plisyk, E Pavlikova… - 2021 - covid19.neicon.ru
Introduction The aim of this study was to assess the efficacy and safety of a combination of
bromhexine at a dose of 8 mg 4 times a day and spironolactone 50 mg per day in patients …
bromhexine at a dose of 8 mg 4 times a day and spironolactone 50 mg per day in patients …
Результаты открытого проспективного контролируемого сравнительного исследования по лечению новой коронавирусной инфекции (COVID-19): Бромгексин …
ВЮ Мареев, ЯА Орлова, АГ Плисюк, ЕП Павликова… - Кардиология, 2020 - lib.ossn.ru
Результаты открытого проспективного контролируемого сравнительного исследования по
лечению новой коронавирусной инфекции (COVID-19): Бромгексин И Спиронолактон для …
лечению новой коронавирусной инфекции (COVID-19): Бромгексин И Спиронолактон для …
Setomimycin as a potential molecule for COVID‑19 target: in silico approach and in vitro validation
RS Manhas, H Tiwari, M Noor, A Ahmed… - Molecular Diversity, 2023 - Springer
COVID-19 pandemic caused by the SARS-CoV-2 virus has led to a worldwide crisis. In view
of emerging variants time to time, there is a pressing need of effective COVID-19 …
of emerging variants time to time, there is a pressing need of effective COVID-19 …
An In Silico Design of Peptides Targeting the S1/S2 Cleavage Site of the SARS-CoV-2 Spike Protein
C Ho, WFWM Nazarie, PC Lee - Viruses, 2023 - mdpi.com
SARS-CoV-2, responsible for the COVID-19 pandemic, invades host cells via its spike
protein, which includes critical binding regions, such as the receptor-binding domain (RBD) …
protein, which includes critical binding regions, such as the receptor-binding domain (RBD) …
A review of the progress of COVID-19 vaccine development
A coronavirus disease pandemic (COVID-19) is still a global problem with not sufficient
evidence of a declining pattern caused by severe acute respiratory syndrome coronavirus 2 …
evidence of a declining pattern caused by severe acute respiratory syndrome coronavirus 2 …