Recent advances on cyclodepsipeptides: biologically active compounds for drug research

SX Liu, SY Ou-Yang, YF Lu, CL Guo, SY Dai… - Frontiers in …, 2023 - frontiersin.org
Cyclodepsipeptides are a large family of peptide-related natural products consisting of
hydroxy and amino acids linked by amide and ester bonds. A number of cyclodepsipeptides …

Structures and Biological Activities of Secondary Metabolites from Xylaria spp.

W Chen, M Yu, S Chen, T Gong, L Xie, J Liu, C Bian… - Journal of Fungi, 2024 - mdpi.com
The fungus genus Xylaria is an important source of drug discoveries in scientific fields and in
the pharmaceutical industry due to its potential to produce a variety of structured novel and …

Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity

X Zhang, Y Fan, K Ye, X Pan, X Ma, H Ai, B Shi, J Liu - Pharmaceuticals, 2023 - mdpi.com
Six previously undescribed cytochalasins, Curtachalasins X1–X6 (1–6), together with six
known compounds (7–12) were isolated from the endophytic fungus Xylaria curta E10 …

Halogenase-targeted genome mining leads to the discovery of (±) pestalachlorides A1a, A2a, and their atropisomers

M Luo, M Wang, S Chang, N He, G Shan, Y Xie - Antibiotics, 2022 - mdpi.com
Genome mining has become an important tool for discovering new natural products and
identifying the cryptic biosynthesis gene clusters. Here, we utilized the flavin-dependent …

Nocaviogua A and B: two lipolanthines from root-nodule-associated Nocardia sp.

S Chang, Y Luo, N He, X Huang, M Chen… - Frontiers in …, 2023 - frontiersin.org
Nocaviogua A (1) and B (2), two lipolanthines featuring a non-canonical avionin (Avi)-
containing macrocycle and a long acyl chain, were identified from the mutualistic …

Theory and computation of nuclear shielding

T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …

Pairing comparative genomics with tandem mass-based molecular networking allows to highly efficient discovery of nonribosomal peptides from Nocardia spp.

S Chang, Y Luo, M Wang, N He, M Chen… - … of Chromatography A, 2023 - Elsevier
Microbial natural products, particularly nonribosomal peptides (NRPs), have attracted
significant attention due to their structural diversity and therapeutic potential. Nocardia, a …

Involvement of a Noncanonical Polyketide Synthase–Nonribosomal Peptide Synthetase Hybrid in the Biosynthesis of Sterol-C4-methyl Oxidase Inhibitor PF1163A

Q Ji, X Wei, S Liu, Y Matsuda - Organic Letters, 2025 - ACS Publications
PF1163A (1) is a fungal metabolite that inhibits sterol-C4-methyl oxidase. In this study, we
identified the biosynthetic gene cluster of 1 and elucidated its biosynthetic pathway through …

Bioactivity-Based Molecular Networking-Guided Isolation of Epicolidines A–C from the Endophytic Fungus Epicoccum sp. 1-042

S Chang, Y Li, X Huang, N He, M Wang… - Journal of Natural …, 2024 - ACS Publications
Bioactivity-based molecular networking-guided fractionation enabled the isolation of three
new polycyclic tetramic acids bearing cis-decalin, epicolidines A–C (1–3), along with one …

Endolichenic Fungi: A Promising Medicinal Microbial Resource to Discover Bioactive Natural Molecules—An Update

W Zhang, Q Ran, H Li, H Lou - Journal of Fungi, 2024 - mdpi.com
Lichens are some of the most unique fungi and are naturally encountered as symbiotic
biological organisms that usually consist of fungal partners (mycobionts) and photosynthetic …