Since the last century, advances in healthcare, housing, and education have led to an
increase in life expectancy. Longevity is accompanied by a higher prevalence of age-related …

The skin and the oral mucosa represent interfaces to the environment that are constantly
exposed to pathogens and harmless foreign antigens such as commensal bacteria. Both …

As the most potent cells activating and polarizing naive T cells, dendritic cells (DCs) are of
major importance in the induction of immunity and tolerance. DCs are a heterogeneous …

In murine periodontitis, the T helper (Th) 17 response against Porphyromonas gingivalis in
cervical lymph node is abrogated by diphtheria toxin–driven depletion of Langerhans cells …

Older age is associated with reduced immune function. Our aim was to study how age
affects the development of apical periodontitis (AP). AP was induced in two age groups of …

The first encounter of mucosal barriers with the microbiota initiates host–microbiota
feedback loops instructing the tailored development of both the immune system and …

In recent years, there has been increasing attention towards understanding the relationship
between age‐related alterations in the oral microbiota and age‐associated diseases, with …

As integral components of the immune microenvironment, tissue resident macrophages
(TRMs) represent a self-renewing and long-lived cell population that plays crucial roles in …

Older age is associated with reduced immune function. Our aim was to study how age
affects the development of apical periodontitis (AP). AP was induced in two age groups of …