Hyaluronan (HA) is a linear nonsulfated glycosaminoglycan of the extracellular matrix that
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …

Hyaluronan is a straight chain, glycosaminoglycan polymer of the extracellular matrix
composed of repeating units of the disaccharide [-d-glucuronic acid-β1, 3-N-acetyl-d …

Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid
(sHA) produced during inflammation have been shown to be potent activators of …

The ubiquitous glycosaminoglycan (GAG) 1 hyaluronan has diverse biological roles in
vertebrates. These include acting as a vital structural component of connective tissues, the …

Objective To determine whether endogenous synthesis of new extracellular matrix may
contribute to the degree and duration of clinical benefits derived from cross-linked …

CD44 is the primary cell surface receptor for the extracellular matrix glycosaminoglycan
hyaluronan. Here we determined the relative avidities of unlabeled hyaluronan preparations …

Hyaluronan was first described as the mucus of the vitreous body of the eye (1). Its deduced
structure revealed an acidic glycosaminoglycan made entirely of a repeating disaccharide …

The extracellular matrix component hyaluronan (HA) exists physiologically as a high mw
polymer but is cleaved at sites of inflammation, where it will be contacted by dendritic cells …

Hyaluronic acid (hyaluronan), a naturally occurring polymer within the skin, has been
extensively studied since its discovery in 1934. It has been used in a wide range of medical …

CD44 is a major cell surface receptor for the large polydisperse glycosaminoglycan
hyaluronan (HA). Binding of the long and flexible HA chains is thought to be stabilized by the …