Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer
AG Tavianatou, I Caon, M Franchi… - The FEBS …, 2019 - Wiley Online Library
Hyaluronan (HA) is a linear nonsulfated glycosaminoglycan of the extracellular matrix that
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …
Hyaluronan fragments: an information-rich system
R Stern, AA Asari, KN Sugahara - European journal of cell biology, 2006 - Elsevier
Hyaluronan is a straight chain, glycosaminoglycan polymer of the extracellular matrix
composed of repeating units of the disaccharide [-d-glucuronic acid-β1, 3-N-acetyl-d …
composed of repeating units of the disaccharide [-d-glucuronic acid-β1, 3-N-acetyl-d …
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4
C Termeer, F Benedix, J Sleeman, C Fieber… - The Journal of …, 2002 - rupress.org
Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid
(sHA) produced during inflammation have been shown to be potent activators of …
(sHA) produced during inflammation have been shown to be potent activators of …
Hyaluronan-binding proteins: tying up the giant
AJ Day, GD Prestwich - Journal of Biological Chemistry, 2002 - ASBMB
The ubiquitous glycosaminoglycan (GAG) 1 hyaluronan has diverse biological roles in
vertebrates. These include acting as a vital structural component of connective tissues, the …
vertebrates. These include acting as a vital structural component of connective tissues, the …
In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin
Objective To determine whether endogenous synthesis of new extracellular matrix may
contribute to the degree and duration of clinical benefits derived from cross-linked …
contribute to the degree and duration of clinical benefits derived from cross-linked …
Hyaluronan binding by cell surface CD44
J Lesley, VC Hascall, M Tammi, R Hyman - Journal of Biological Chemistry, 2000 - ASBMB
CD44 is the primary cell surface receptor for the extracellular matrix glycosaminoglycan
hyaluronan. Here we determined the relative avidities of unlabeled hyaluronan preparations …
hyaluronan. Here we determined the relative avidities of unlabeled hyaluronan preparations …
Hyaluronan and homeostasis: a balancing act
Hyaluronan was first described as the mucus of the vitreous body of the eye (1). Its deduced
structure revealed an acidic glycosaminoglycan made entirely of a repeating disaccharide …
structure revealed an acidic glycosaminoglycan made entirely of a repeating disaccharide …
Oligosaccharides of hyaluronan are potent activators of dendritic cells
CC Termeer, J Hennies, U Voith, T Ahrens… - The Journal of …, 2000 - journals.aai.org
The extracellular matrix component hyaluronan (HA) exists physiologically as a high mw
polymer but is cleaved at sites of inflammation, where it will be contacted by dendritic cells …
polymer but is cleaved at sites of inflammation, where it will be contacted by dendritic cells …
The role of hyaluronic acid in wound healing: assessment of clinical evidence
RD Price, S Myers, IM Leigh, HA Navsaria - American journal of clinical …, 2005 - Springer
Hyaluronic acid (hyaluronan), a naturally occurring polymer within the skin, has been
extensively studied since its discovery in 1934. It has been used in a wide range of medical …
extensively studied since its discovery in 1934. It has been used in a wide range of medical …
Analysis of CD44-hyaluronan interactions in an artificial membrane system: insights into the distinct binding properties of high and low molecular weight hyaluronan
PM Wolny, S Banerji, C Gounou, AR Brisson… - Journal of Biological …, 2010 - ASBMB
CD44 is a major cell surface receptor for the large polydisperse glycosaminoglycan
hyaluronan (HA). Binding of the long and flexible HA chains is thought to be stabilized by the …
hyaluronan (HA). Binding of the long and flexible HA chains is thought to be stabilized by the …