White adipose tissue (WAT) is innervated by the sympathetic nervous system (SNS) and its
activation is necessary for lipolysis. WAT parasympathetic innervation is not supported. Fully …

The sodium-glucose cotransporter 2 (SGLT2) inhibitors have become an integral part of
clinical practice guidelines to slow the progression of CKD in patients with and without …

Adipose tissue is now recognised as a highly active metabolic and endocrine organ. Great
strides have been made in uncovering the multiple functions of the adipocyte in cellular and …

Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …

Leptin is an adipocyte-derived hormone that plays a key role in the regulation of body weight
through its actions on appetite and metabolism. Leptin also increases sympathetic nerve …

Although visceral obesity is recognized as a risk factor for cardiovascular diseases (CVDs),
the efficacy of omental fat removal in CVD treatment is still controversial. There is a need to …

Obesity, a major healthcare issue, is associated with significant cardiovascular morbidities,
including hypertension and atherosclerosis. Numerous intensive studies conducted this …

Leptin is a 16-kDa protein secreted by white adipose tissue that is primarily involved in the
regulation of food intake and energy expenditure. Plasma leptin concentration is …

A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it
contributes to energy homeostasis and provides insulation for internal organs. Adipocytes …

Leptin, an adipocyte secreted hormone, acts in the hypothalamus to inhibit appetite and
promote thermogenic metabolism, thereby reducing adiposity and body weight. Leptin has …