Cellular and structural bases of chronic obstructive pulmonary disease

M Saetta, G Turato, P Maestrelli, CE Mapp… - American journal of …, 2001 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is defined as a disease state characterized
by poorly reversible airflow limitation that is usually both progressive and associated with an …

[HTML][HTML] Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis

Y Wang, S Liao, Z Pan, S Jiang, J Fan, S Yu… - Free Radical Biology …, 2022 - Elsevier
Background Redox imbalance is an vital mechanism for COPD. At present, insufficient
researches have been conducted on the protective effect of hydrogen sulfide (H 2 S) on PM …

Dihydroquercetin suppresses cigarette smoke induced ferroptosis in the pathogenesis of chronic obstructive pulmonary disease by activating Nrf2-mediated pathway

X Liu, Y Ma, L Luo, D Zong, H Li, Z Zeng, Y Cui… - Phytomedicine, 2022 - Elsevier
Background Dihydroquercetin (DHQ) is a flavonoid with strong anti-inflammatory and
antioxidant effects. However, its protective activity against cigarette smoke-induced …

The history of COPD

TL Petty - International journal of chronic obstructive pulmonary …, 2006 - Taylor & Francis
The evolution of knowledge concerning COPD and its components–emphysema, chronic
bronchitis, and asthmatic bronchitis–covers 200 years. The stethoscope and spirometer …

Alveolar wall apoptosis causes lung destruction and emphysematous changes

K Aoshiba, N Yokohori, A Nagai - American journal of respiratory …, 2003 - atsjournals.org
Pulmonary emphysema is characterized by alveolar wall destruction and airspace
enlargement. Recent evidence indicates that epithelial or endothelial apoptosis may be …

Nrf2‐deficient mice are highly susceptible to cigarette smoke‐induced emphysema

T Iizuka, Y Ishii, K Itoh, T Kiwamoto, T Kimura… - Genes to …, 2005 - Wiley Online Library
Inflammation, protease/anti‐protease imbalance and oxidative stress play important roles in
the pathogenesis of emphysema. Nrf2 counteracts oxidative tissue damage and …

Emphysema: definition, imaging, and quantification.

WM Thurlbeck, NL Müller - AJR. American journal of …, 1994 - Am Roentgen Ray Soc
This review will discuss imaging of the chest in patients with pulmonary emphysema.
Imaging findings must be related to the structure of the lung because emphysema is defined …

The senile lung: comparison with normal and emphysematous lungs 1. Structural aspects

EK Verbeken, M Cauberghs, I Mertens, J Clement… - Chest, 1992 - Elsevier
As part of a study of the structural-functional correlations of excised human lungs obtained at
autopsy, the parenchyma and peripheral airways were examined by means of morphometric …

Airway inflammation in chronic obstructive pulmonary disease

M Saetta - American journal of respiratory and critical care …, 1999 - atsjournals.org
AM J RESPIR CRIT CARE MED 1999; 160: S17− S20. Cigarette smoking causes an
inflammatory process in the central airways, peripheral airways, and lung parenchyma, even …

[引用][C] Clinical relevance of airway remodelling in airway diseases

AL James, S Wenzel - European Respiratory Journal, 2007 - Eur Respiratory Soc