[HTML][HTML] Larval zebrafish as a model for mechanistic discovery in mental health

JXM Tan, RJW Ang, CL Wee - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Animal models are essential for the discovery of mechanisms and treatments for
neurological disorders. However, complex mental health disorders such as depression and …

[HTML][HTML] Backpropagation with sparsity regularization for spiking neural network learning

Y Yan, H Chu, Y Jin, Y Huan, Z Zou… - Frontiers in …, 2022 - frontiersin.org
The spiking neural network (SNN) is a possible pathway for low-power and energy-efficient
processing and computing exploiting spiking-driven and sparsity features of biological …

[HTML][HTML] Sharing begins at home: How continuous and ubiquitous FAIRness can enhance research productivity and data reuse

W Dempsey, I Foster, S Fraser… - Harvard data science …, 2022 - ncbi.nlm.nih.gov
The broad sharing of research data is widely viewed as critical for the speed, quality,
accessibility, and integrity of science. Despite increasing efforts to encourage data sharing …

Synaptic input and Ca2+ activity in zebrafish oligodendrocyte precursor cells contribute to myelin sheath formation

J Li, TG Miramontes, T Czopka, KR Monk - Nature Neuroscience, 2024 - nature.com
In the nervous system, only one type of neuron–glial synapse is known to exist: that between
neurons and oligodendrocyte precursor cells (OPCs), yet their composition, assembly …

Quantitative fluorescence analysis reveals dendrite-specific thalamocortical plasticity in L5 pyramidal neurons during learning

A Ray, JA Christian, MB Mosso, E Park… - Journal of …, 2023 - Soc Neuroscience
High-throughput anatomic data can stimulate and constrain new hypotheses about how
neural circuits change in response to experience. Here, we use fluorescence-based …

A brain-wide analysis maps structural evolution to distinct anatomical module

RA Kozol, AJ Conith, A Yuiska, A Cree-Newman… - Elife, 2023 - elifesciences.org
The vertebrate brain is highly conserved topologically, but less is known about
neuroanatomical variation between individual brain regions. Neuroanatomical variation at …

Epigenetically distinct synaptic architecture in clonal compartments in the teleostean dorsal pallium

Y Isoe, R Nakamura, S Nonaka, Y Kamei, T Okuyama… - Elife, 2023 - elifesciences.org
The dorsal telencephalon (ie the pallium) exhibits high anatomical diversity across
vertebrate classes. The non-mammalian dorsal pallium accommodates various …

[HTML][HTML] Sleep pressure modulates single-neuron synapse number in zebrafish

A Suppermpool, DG Lyons, E Broom, J Rihel - Nature, 2024 - nature.com
Sleep is a nearly universal behaviour with unclear functions. The synaptic homeostasis
hypothesis proposes that sleep is required to renormalize the increases in synaptic number …

How the Brain Becomes the Mind: Can Thermodynamics Explain the Emergence and Nature of Emotions?

É Déli, JF Peters, Z Kisvárday - Entropy, 2022 - mdpi.com
The neural systems' electric activities are fundamental for the phenomenology of
consciousness. Sensory perception triggers an information/energy exchange with the …

Inhibition of late mRNA synthesis in the hippocampus impairs consolidation and reconsolidation of spatial memory in male rats

WC da Silva, JS Bonini - Neurobiology of Learning and Memory, 2022 - Elsevier
It has already been shown that both consolidation and reconsolidation of long-term
memories require protein synthesis and de novo gene transcription immediately after …