Magnesium metabolism in type 2 diabetes mellitus, metabolic syndrome and insulin resistance

M Barbagallo, LJ Dominguez - Archives of biochemistry and biophysics, 2007 - Elsevier
Type 2 diabetes is characterized by cellular and extracellular Mg depletion. Epidemiologic
studies showed a high prevalence of hypomagnesaemia and lower intracellular Mg …

Role of magnesium in hypertension

B Sontia, RM Touyz - Archives of biochemistry and biophysics, 2007 - Elsevier
Magnesium affects blood pressure by modulating vascular tone and reactivity. It acts as a
calcium channel antagonist, it stimulates production of vasodilator prostacyclins and nitric …

Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension

RM Touyz - American Journal of Physiology-Heart and …, 2008 - journals.physiology.org
Magnesium, an essential intracellular cation, is critically involved in many biochemical
reactions involved in the regulation of vascular tone and integrity. Decreased magnesium …

[HTML][HTML] Magnesium and ischemic heart disease: a review of epidemiological, experimental, and clinical evidences

K Ueshima - Magnesium Research, 2005 - jle.com
Magnesium (Mg) is the second most abundant intracellular cation (next to potassium) and
the fourth most abundant cation in the body. Mg is a co-factor for more than 300 cellular …

Magnesium attenuates chronic hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat model of diabetic neuropathic pain

LJ Rondón, AM Privat, L Daulhac… - The Journal of …, 2010 - Wiley Online Library
Neuropathic pain is a common diabetic complication affecting 8–16% of diabetic patients. It
is characterized by aberrant symptoms of spontaneous and stimulus‐evoked pain including …

Magnesium upregulates insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide-induced type-2 diabetic rats

AO Morakinyo, TA Samuel, DA Adekunbi - Endocrine regulations, 2018 - sciendo.com
Objective. We investigated the effects of magnesium supplementation on glucose tolerance,
insulin sensitivity, oxidative stress as well as the concentration of insulin receptor and …

Effect of oral magnesium sulfate administration on blood pressure and lipid profile in streptozocin diabetic rat

N Soltani, M Keshavarz, AR Dehpour - European Journal of Pharmacology, 2007 - Elsevier
Approximately one-third of patients with type 1 diabetes develop a variety of complications
as a result of mechanisms that are not completely understood. However, insufficient …

Role of Cav1.2 L-type Ca2+ channels in vascular tone: effects of nifedipine and Mg2+

J Zhang, R Berra-Romani… - American Journal …, 2007 - journals.physiology.org
Ca2+ entry via L-type voltage-gated Ca2+ channels (LVGCs) is a key factor in generating
myogenic tone (MT), as dihydropyridines (DHPs) and other LVGC blockers, including Mg2+ …

Protective effect of magnesium on renal function in STZ-induced diabetic rats

MR Parvizi, M Parviz, SM Tavangar, N Soltani… - Journal of Diabetes & …, 2014 - Springer
Background Diabetic nephropathy is a serious complication of T1D (type one diabetes
mellitus). Persistent hyperglycemia and subsequent hypomagnesemia is believed to …

The Benefits of Nanosized Magnesium Oxide in Fish Megalobrama amblycephala: Evidence in Growth Performance, Redox Defense, Glucose Metabolism, and …

L Zhang, Z Liu, Y Deng, C He, W Liu, X Li - Antioxidants, 2023 - mdpi.com
This study evaluated the effects of dietary magnesium oxide nanoparticles (MgO NPs) on the
growth, redox defense, glucose metabolism, and magnesium homeostasis in blunt snout …