A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine

S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …

Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities

A Hassanzadeh, HS Rahman, A Markov… - Stem cell research & …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) and their widespread biomedical
applications have attracted great consideration from the scientific community around the …

Exosomes derived from pro‐inflammatory bone marrow‐derived mesenchymal stem cells reduce inflammation and myocardial injury via mediating macrophage …

R Xu, F Zhang, R Chai, W Zhou, M Hu… - Journal of cellular …, 2019 - Wiley Online Library
Exosomes are served as substitutes for stem cell therapy, playing important roles in
mediating heart repair during myocardial infarction injury. Evidence have indicated that …

[HTML][HTML] Mesenchymal stem cells-derived extracellular vesicles, via miR-210, improve infarcted cardiac function by promotion of angiogenesis

NA Wang, C Chen, D Yang, Q Liao, H Luo… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Mesenchymal stem cells (MSCs) exert therapeutic effect on treating acute myocardial
infarction. Recent evidence showed that paracrine function rather than direct differentiation …

Cardioprotective microRNAs: Lessons from stem cell-derived exosomal microRNAs to treat cardiovascular disease

AS Moghaddam, JT Afshari, SA Esmaeili, E Saburi… - Atherosclerosis, 2019 - Elsevier
The stem cell-based therapy has emerged as a promising therapeutic strategy for treating
cardiovascular ischemic diseases (CVIDs), such as myocardial infarction (MI). However …

microRNA-141-3p-containing small extracellular vesicles derived from epithelial ovarian cancer cells promote endothelial cell angiogenesis through activating the …

S Masoumi-Dehghi, S Babashah… - Journal of cell …, 2020 - Springer
Paracrine signaling between tumor and surrounding stromal cells is critical for the
maintenance of tumor microenvironment during ovarian cancer progression. Small …

Urinary extracellular vesicles carrying klotho improve the recovery of renal function in an acute tubular injury model

C Grange, E Papadimitriou, V Dimuccio, C Pastorino… - Molecular Therapy, 2020 - cell.com
Acute kidney injury, defined by a rapid deterioration of renal function, is a common
complication in hospitalized patients. Among the recent therapeutic options, the use of …

Functional recovery in photo-damaged human dermal fibroblasts by human adipose-derived stem cell extracellular vesicles

JS Choi, WL Cho, YJ Choi, JD Kim… - Journal of …, 2019 - Taylor & Francis
Ultraviolet-B (UVB) irradiation causes imbalance between dermal matrix synthesis and
degradation through aberrant upregulation of matrix metalloproteinases (MMPs), which …

[HTML][HTML] Immunosuppressive effect of exosomes from mesenchymal stromal cells in defined medium on experimental colitis

ZJ Ma, YH Wang, ZG Li, Y Wang, BY Li… - … journal of stem …, 2019 - synapse.koreamed.org
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Preparation of engineered extracellular vesicles derived from human umbilical cord mesenchymal stem cells with ultrasonication for skin rejuvenation

L Wang, KK Abhange, Y Wen, Y Chen, F Xue… - ACS …, 2019 - ACS Publications
Extracellular vesicles (EVs) are lipid-bilayer-enclosed vesicles of submicron size that are
secreted by various cells. As mediators of intercellular communication, EVs can alter the …