Sleep—A brain-state serving systems memory consolidation

S Brodt, M Inostroza, N Niethard, J Born - Neuron, 2023 - cell.com
Although long-term memory consolidation is supported by sleep, it is unclear how it differs
from that during wakefulness. Our review, focusing on recent advances in the field, identifies …

[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits

J Nagai, X Yu, T Papouin, E Cheong, MR Freeman… - Neuron, 2021 - cell.com
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

Fast-specific fluorescent probes to visualize norepinephrine signaling pathways and its flux in the epileptic mice brain

H Yan, Y Wang, F Huo, C Yin - Journal of the American Chemical …, 2023 - ACS Publications
Norepinephrine (NE) is synthesized in the locus coeruleus and widely projected throughout
the brain and spinal cord. It regulates various actions and consciousness linked to a variety …

Spatiotemporal dynamics of noradrenaline during learned behaviour

V Breton-Provencher, GT Drummond, J Feng, Y Li… - Nature, 2022 - nature.com
Noradrenaline released from the locus coeruleus (LC) is a ubiquitous neuromodulator,,–that
has been linked to multiple functions including arousal,,–, action and sensory gain,–, and …

Noradrenergic modulation of rhythmic neural activity shapes selective attention

MJ Dahl, M Mather, M Werkle-Bergner - Trends in cognitive sciences, 2022 - cell.com
During moments involving selective attention, the thalamus orchestrates the preferential
processing of prioritized information by coordinating rhythmic neural activity within a …

Tonic and burst-like locus coeruleus stimulation distinctly shift network activity across the cortical hierarchy

C Grimm, SN Duss, M Privitera, BR Munn… - Nature …, 2024 - nature.com
Noradrenaline (NA) release from the locus coeruleus (LC) changes activity and connectivity
in neuronal networks across the brain, modulating multiple behavioral states. NA release is …

[HTML][HTML] Noradrenergic and cholinergic systems take centre stage in neuropsychiatric diseases of ageing

IF Orlando, JM Shine, TW Robbins, JB Rowe… - Neuroscience & …, 2023 - Elsevier
Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …

When the locus coeruleus speaks up in sleep: recent insights, emerging perspectives

A Osorio-Forero, N Cherrad, L Banterle… - International journal of …, 2022 - mdpi.com
For decades, numerous seminal studies have built our understanding of the locus coeruleus
(LC), the vertebrate brain's principal noradrenergic system. Containing a numerically small …

Astrocytes control sensory acuity via tonic inhibition in the thalamus

H Kwak, W Koh, S Kim, K Song, JI Shin, JM Lee… - Neuron, 2020 - cell.com
Sensory discrimination is essential for survival. However, how sensory information is finely
controlled in the brain is not well defined. Here, we show that astrocytes control tactile acuity …

Locus coeruleus-norepinephrine modulation of sensory processing and perception: A focused review

J McBurney-Lin, J Lu, Y Zuo, H Yang - Neuroscience & Biobehavioral …, 2019 - Elsevier
The locus coeruleus-norepinephrine (LC-NE) system is involved in many brain functions
and neurological disorders. In this review we discuss how LC-NE signaling affects the …