[HTML][HTML] MICAL-mediated oxidation of actin and its effects on cytoskeletal and cellular dynamics

S Rajan, JR Terman, E Reisler - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Actin and its dynamic structural remodelings are involved in multiple cellular functions,
including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle …

[HTML][HTML] Current status for controlling the overlooked caprine fasciolosis

G Zerna, TW Spithill, T Beddoe - Animals, 2021 - mdpi.com
Simple Summary Retaining sustainable agricultural systems is essential to feed the
expanding population. Helminth parasite infections impact livestock production values and …

[HTML][HTML] RAB10 promotes breast cancer proliferation migration and invasion predicting a poor prognosis for breast cancer

J Zhuo, J Han, Y Zhao, R Hao, C Shen, H Li, L Dai… - Scientific Reports, 2023 - nature.com
RAB10, a member of the small GTPase family, has complex biological functions, but its role
in breast cancer (BC) remains unclear. The aim of this study was to investigate the …

[HTML][HTML] Comparative proteomics of adult Paragonimus kellicotti excretion/secretion products released in vitro or present in the lung cyst nodule

LS Di Maggio, KC Curtis… - PLoS neglected …, 2022 - journals.plos.org
Paragonimus kellicotti is a zoonotic lung fluke infection, the agent of North American
paragonimiasis, and an excellent model for other Paragonimus infections. The …

[HTML][HTML] Proteomic differences between extracellular vesicles and extracellular vesicle-depleted excretory/secretory products of barber's pole worm

F Wu, X Chen, Z Du, Y Chen, D Tong, J Zhang… - Parasites & …, 2024 - Springer
Background Components of excretory/secretory products (ESPs) of helminths have been
proposed as vaccine targets and shown to play a role in modulating host immune responses …

[HTML][HTML] The Multitasking Fasciola gigantica Cathepsin B Interferes With Various Functions of Goat Peripheral Blood Mononuclear Cells in vitro

D Chen, AL Tian, JL Hou, JX Li, XW Tian… - Frontiers in …, 2019 - frontiersin.org
Cathepsin B, a lysosomal cysteine protease, is thought to be involved in the pathogenesis of
Fasciola gigantica infection, but its exact role remains unclear. In the present study, a …

Immune modulation of goat monocytes by Fasciola gigantica Legumain-1 protein (Fg-LGMN-1)

M Ehsan, RS Hu, M Wang, JL Hou, M Rashid… - Experimental …, 2024 - Elsevier
Legumains belonging to C_13 peptidase family of proteins, and are ubiquitously
disseminated among all vertebrate and invertebrate organisms, and have been implicated in …

[HTML][HTML] Fasciola gigantica tegumental calcium-binding EF-hand protein 4 exerts immunomodulatory effects on goat monocytes

M Ehsan, RS Hu, JL Hou, HM Elsheikha, XD Li… - Parasites & …, 2021 - Springer
Abstract Background The liver fluke Fasciola gigantica secretes excretory-secretory proteins
during infection to mediate its interaction with the host. In this study, we investigated the …

Proteomic analysis of the excretory-secretory products from Strongyloides venezuelensis infective larvae: new insights for the immunodiagnosis of human …

WH Roldan Gonzales, GR Coelho, DC Pimenta… - Parasitology …, 2022 - Springer
Serodiagnosis of human strongyloidiasis is a practical alternative to parasitological methods
due to its high sensitivity. However, cross-reactivity with other helminth infections limits its …

[HTML][HTML] Modulation of the Functions of Goat Peripheral Blood Mononuclear Cells by Fasciola gigantica Thioredoxin Peroxidase In Vitro

AL Tian, X Tian, D Chen, M Lu, G Calderón-Mantilla… - Pathogens, 2020 - mdpi.com
The liver fluke Fasciola gigantica has a remarkable ability to establish a long-term infection
within the hepatobiliary system of the mammalian definitive host. F. gigantica achieves this …