As our understanding of the human microbiome progresses, so does the need for natural
experimental animal models that promote a mechanistic understanding of beneficial …

Mercury (Hg) and its organic compounds, especially monomethylmercury (MeHg), cause
major damage to the ecosystem and human health. In surface water or sediments …

Vibrio cholerae causes cholera, an important cause of death worldwide. A fuller
understanding of how virulence is regulated offers the potential for developing virulence …

Bioluminescence, the emission of light catalysed by luciferases, has evolved in many taxa
from bacteria to vertebrates and is predominant in the marine environment. It is now well …

The structure of the dimeric holo–fumarate and nitrate reduction regulator (FNR) from
Aliivibrio fischeri has been solved at 2.65 Å resolution. FNR globally controls the transition …

Vibrio fischeri is a bioluminescent, Gram-negative marine bacterium that can be found free
living and in a mutualistic association with certain squids and fishes. Over the past decades …

Vibrio fischeri serves as a valuable model of bacterial bioluminescence, its regulation, and
its functional significance. Light output varies more than 10,000-fold in wild-type isolates …

The well-known Crp/Fnr family regulator Fnr has long been recognized as an oxygen sensor
to regulate multiple biological processes, including the switch between aerobic/anaerobic …

The Escherichia coli fumarate and nitrate reduction (FNR) regulator acts as the cell's master
switch for the transition between anaerobic and aerobic respiration, controlling the …

Many proteobacteria modulate a suite of catabolic genes using the second messenger cyclic
3′, 5′-AMP (cAMP) and the cAMP receptor protein (CRP). Together, the cAMP-CRP …