[HTML][HTML] Enhanced CRISPR/Cas12a-based quantitative detection of nucleic acids using double emulsion droplets

Y Zhang, H Liu, Y Nakagawa, Y Nagasaka… - Biosensors and …, 2024 - Elsevier
Pairing droplet microfluidics and CRISPR/Cas12a techniques creates a powerful solution for
the detection and quantification of nucleic acids at the single-molecule level, due to its …

Flexible droplet transportation and coalescence via controllable thermal fields

K Zhang, W Xiang, J Liu, Z Xie - Analytica chimica acta, 2023 - Elsevier
Flexible droplet transportation and coalescence are significant for lots of applications such
as material synthesis and analytical detection. Herein, we present an effective method for …

Versatility and stability optimization of flow-focusing droplet generators via quality metric-driven design automation

D McIntyre, A Lashkaripour, D Arguijo, P Fordyce… - Lab on a Chip, 2023 - pubs.rsc.org
Droplet generation is a fundamental component of droplet microfluidics, compartmentalizing
biological or chemical systems within a water-in-oil emulsion. As adoption of droplet …

Multiple emulsions: A new level-set based two-and-three dimensional simulation of multiphase immiscible flows for droplet formation

M Oveysi, MMK Khani, V Bazargan, A Nejat… - International Journal of …, 2024 - Elsevier
The present paper introduces a numerical approach based on the level-set framework to
simulate multiphase flow in the context of multiple emulsion formation. The present …

Grease the gears: how lubrication of syringe pumps impacts microfluidic flow precision

M Leuthner, O Hayden - Lab on a Chip, 2024 - pubs.rsc.org
Pumps are indispensable for analytical applications and ensure controlled fluid movement.
Syringe pumps are among today's most prevalent liquid delivery systems, especially for high …

Microfluidics-driven high-throughput phenotyping and screening in synthetic biology: from single cells to cell-free systems

T Kim, M Ko, E Rha, H Kim, H Lee - Biotechnology and Bioprocess …, 2024 - Springer
The interdisciplinary nature of synthetic biology merges engineering principles with biology
and provides innovative solutions for issues in the biomanufacturing industry. To develop …

[HTML][HTML] Design automation of microfluidic single and double emulsion droplets with machine learning

A Lashkaripour, DP McIntyre, SGK Calhoun… - Nature …, 2024 - nature.com
Droplet microfluidics enables kHz screening of picoliter samples at a fraction of the cost of
other high-throughput approaches. However, generating stable droplets with desired …

Binary fluid flow simulations with free energy lattice Boltzmann methods

S Simonis, J Nguyen, SJ Avis, W Dörfler… - … Dynamical Systems-S, 2023 - aimsciences.org
We use free energy lattice Boltzmann methods to simulate shear and extensional flows of a
binary fluid in two and three dimensions. To this end, two classical configurations are …

[PDF][PDF] Lattice Boltzmann Methods for Partial Differential Equations

S Simonis - 2023 - core.ac.uk
Lattice Boltzmann methods provide a robust and highly scalable numerical technique in
modern computational fluid dynamics. Besides the discretization procedure, the relaxation …

Binary mixture flow with free energy lattice Boltzmann methods

S Simonis, J Nguyen, SJ Avis, W Dörfler… - arXiv preprint arXiv …, 2022 - arxiv.org
We use free energy lattice Boltzmann methods (FRE LBM) to simulate shear and
extensional flow of a binary mixture in two and three dimensions. To this end, two classical …