Extraction and fractionation of microalgae-based protein products

L Soto-Sierra, P Stoykova, ZL Nikolov - Algal Research, 2018 - Elsevier
Microalgae are a valuable source of proteins that can be utilized as functional, nutritional
and therapeutic commodities. While process optimization and integration are still required to …

[HTML][HTML] The cell density effect in animal cell-based bioprocessing: Questions, insights and perspectives

J Lavado-García, P Pérez-Rubio, L Cervera… - Biotechnology …, 2022 - Elsevier
One of the main challenges in the development of bioprocesses based on cell transient
expression is the commonly reported reduction of cell specific productivity at increasing cell …

[图书][B] Electrotechnologies for extraction from food plants and biomaterials

E Vorobiev, N Lebovka - 2008 - Springer
Solvent and pressure extraction are the major unit operations in many food and related
industries (production of sugar, wine, vegetable oils, and fruit juices), recuperation of …

Targeted cellular ablation based on the morphology of malignant cells

JW Ivey, EL Latouche, MB Sano, JH Rossmeisl… - Scientific reports, 2015 - nature.com
Abstract Treatment of glioblastoma multiforme (GBM) is especially challenging due to a
shortage of methods to preferentially target diffuse infiltrative cells and therapy-resistant …

Microscale electroporation: challenges and perspectives for clinical applications

WG Lee, U Demirci, A Khademhosseini - Integrative Biology, 2009 - academic.oup.com
Microscale engineering plays a significant role in developing tools for biological applications
by miniaturizing devices and providing controllable microenvironments for in vitro cell …

Nanofountain probe electroporation (NFP-E) of single cells

W Kang, F Yavari, M Minary-Jolandan… - Nano …, 2013 - ACS Publications
The ability to precisely deliver molecules into single cells is of great interest to biotechnology
researchers for advancing applications in therapeutics, diagnostics, and drug delivery …

Nonendocytic delivery of functional engineered nanoparticles into the cytoplasm of live cells using a novel, high-throughput microfluidic device

J Lee, A Sharei, WY Sim, A Adamo, R Langer… - Nano …, 2012 - ACS Publications
The ability to straightforwardly deliver engineered nanoparticles into the cell cytosol with
high viability will vastly expand the range of biological applications. Nanoparticles could …

Human cardiomyocytes are more susceptible to irreversible electroporation by pulsed electric field than human esophageal cells

M Casciola, D Keck, TK Feaster… - Physiological …, 2022 - Wiley Online Library
Pulse electric field‐based (PEF) ablation is a technique whereby short high‐intensity electric
fields inducing irreversible electroporation (IRE) are applied to various tissues. Here, we …

Pulsed-electric-fields-induced effects in plant tissues: fundamental aspects and perspectives of applications

E Vorobiev, N Lebovka - … for extraction from food plants and biomaterials, 2008 - Springer
The purpose of this contribution is to review the existing approaches to pulsed electric field
(PEF) application as a tool for enhancing the processing of plant tissues. The PEF-treatment …

Improving cancer therapies by targeting the physical and chemical hallmarks of the tumor microenvironment

JW Ivey, M Bonakdar, A Kanitkar, RV Davalos… - Cancer letters, 2016 - Elsevier
Tumors are highly heterogeneous at the patient, tissue, cellular, and molecular levels. This
multi-scale heterogeneity poses significant challenges for effective therapies, which ideally …