Molecular photoswitches in aqueous environments

J Volarić, W Szymanski, NA Simeth… - Chemical Society …, 2021 - pubs.rsc.org
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Recent developments in reversible photoregulation of oligonucleotide structure and function

AS Lubbe, W Szymanski, BL Feringa - Chemical Society Reviews, 2017 - pubs.rsc.org
There is a growing interest in the photoregulation of biological functions, due to the high
level of spatiotemporal precision achievable with light. Additionally, light is non-invasive and …

G-quadruplexes and their ligands: Biophysical methods to unravel G-quadruplex/ligand interactions

T Santos, GF Salgado, EJ Cabrita, C Cruz - Pharmaceuticals, 2021 - mdpi.com
Progress in the design of G-quadruplex (G4) binding ligands relies on the availability of
approaches that assess the binding mode and nature of the interactions between G4 …

Taking orders from light: progress in photochromic bio-materials

J Zhang, J Wang, H Tian - Materials Horizons, 2014 - pubs.rsc.org
Photochromic materials are a family of compounds which undergo photo-reversible
transformations between two different isomers with distinct physical and chemical properties …

A Photoresponsive Stiff‐Stilbene Ligand Fuels the Reversible Unfolding of G‐Quadruplex DNA

MP O'Hagan, S Haldar, M Duchi… - Angewandte Chemie …, 2019 - Wiley Online Library
The polymorphic nature of G‐quadruplex (G4) DNA structures points to a range of potential
applications in nanodevices and an opportunity to control G4 in biological settings. Light is …

Binding and Beyond: What Else Can G‐Quadruplex Ligands Do?

MP O'Hagan, JC Morales… - European Journal of …, 2019 - Wiley Online Library
G‐quadruplexes (G4) are four‐stranded structures formed from guanine‐rich
oligonucleotides. Their defined 3D structures and polymorphic nature set them apart from …

Photoresponsive control of G-Quadruplex DNA systems

J Ramos-Soriano, MC Galan - JACS Au, 2021 - ACS Publications
G-quadruplex (G4) oligonucleotide secondary structures have recently attracted significant
attention as therapeutic targets owing to their occurrence in human oncogene promoter …

Photodependent melting of unmodified DNA using a photosensitive intercalator: a new and generic tool for photoreversible assembly of DNA nanostructures at …

A Bergen, S Rudiuk, M Morel, T Le Saux, H Ihmels… - Nano …, 2016 - ACS Publications
External control of DNA melting and hybridization, a key step in bio-and DNA
nanotechnology, is commonly achieved with temperature. The use of light to direct this …

Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer

NA Simeth, S Kobayashi, P Kobauri, S Crespi… - Chemical …, 2021 - pubs.rsc.org
Short, complementary DNA single strands with mismatched base pairs cannot undergo
spontaneous formation of duplex DNA (dsDNA). Mismatch binding ligands (MBLs) can …

SERS-based biosensor with Raman-active external responsive element for rapid determination of adenosine monophosphate

E Zavyalova, D Tikhonova, G Zhdanov… - Analytica Chimica …, 2022 - Elsevier
Phosphorylated adenosine derivatives are important biological molecules with diverse
biological functions connected with the energetic balance of the cell, biosynthesis of cell …