CTX-M enzymes, the plasmid-mediated cefotaximases, constitute a rapidly growing family of
extended-spectrum β-lactamases (ESBLs) with significant clinical impact. CTX-Ms are found …

Enterobacteriaceae, especially Klebsiella spp. producing extended-spectrum β-lactamases
(ESBLs) such as SHV and TEM types, have been established since the 1980s as a major …

β-Lactams are among the most clinically important antimicrobials in both human and
veterinary medicine. Bacterial resistance to β-lactams has been increasingly observed in …

As more original molecular protocols and subsequent modifications are described in the
literature, it has become difficult for those not directly involved in the development of these …

Background Due to limited therapeutic options, the spread of extended-spectrum beta-
lactamases (ESBLs) have become a major public health concern. We conducted a …

Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) typically cause
nosocomial infections. Previous surveillance in the Calgary Health Region showed that …

Taking readers from the research laboratory to the bedside, this Second Edition compiles
essential information on the pharmacodynamics of all major classes of the antimicrobial …

Background Nosocomial outbreak due to carbapenem-resistant Enterobacteriaceae has
become serious challenge to patient treatment and infection control. We describe an …

ABSTRACT A collection of 40 confirmed isolates of Citrobacter spp., obtained from the
culture of 5,732 clinical samples during 2006 to 2008, was studied for the presence of bla …

Salmonella enterica bla CTX-M-2 and bla CTX-M-9 plasmid backbones from isolates from
Belgium and France were analyzed. The bla CTX-M-2-plasmids from both human and …