[HTML][HTML] Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and …
The plasma membrane in eukaryotic cells contains microdomains that are enriched in
certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form …
certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form …
The extracellular vesicle generation paradox: a bacterial point of view
HM McMillan, MJ Kuehn - The EMBO Journal, 2021 - embopress.org
All bacteria produce secreted vesicles that carry out a variety of important biological
functions. These extracellular vesicles can improve adaptation and survival by relieving …
functions. These extracellular vesicles can improve adaptation and survival by relieving …
[HTML][HTML] Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation
K Rajamäki, J Lappalainen, K Öörni, E Välimäki… - PloS one, 2010 - journals.plos.org
Background Chronic inflammation of the arterial wall is a key element in the pathogenesis of
atherosclerosis, yet the factors that trigger and sustain the inflammation remain elusive …
atherosclerosis, yet the factors that trigger and sustain the inflammation remain elusive …
Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development
L Zhang, J Zhao, SM Lam, L Chen, Y Gao, W Wang… - Nature Cell …, 2024 - nature.com
Lipids are indispensable for energy storage, membrane structure and cell signalling.
However, dynamic changes in various categories of endogenous lipids in mammalian early …
However, dynamic changes in various categories of endogenous lipids in mammalian early …
[HTML][HTML] Cholera toxin subunit B as adjuvant––an accelerator in protective immunity and a break in autoimmunity
T Stratmann - Vaccines, 2015 - mdpi.com
Cholera toxin subunit B (CTB) is the nontoxic portion of cholera toxin. Its affinity to the
monosialotetrahexosylganglioside (GM1) that is broadly distributed in a variety of cell types …
monosialotetrahexosylganglioside (GM1) that is broadly distributed in a variety of cell types …
Structure, biological functions and applications of the AB5 toxins
AB 5 toxins are important virulence factors for several major bacterial pathogens, including
Bordetella pertussis, Vibrio cholerae, Shigella dysenteriae and at least two distinct …
Bordetella pertussis, Vibrio cholerae, Shigella dysenteriae and at least two distinct …
Type II secretion and pathogenesis
M Sandkvist - Infection and immunity, 2001 - Am Soc Microbiol
Extracellular secretion of proteins is regarded as a major virulence mechanism in bacterial
infection. Proteins destined for the extracellular environment of gram-negative bacteria have …
infection. Proteins destined for the extracellular environment of gram-negative bacteria have …
AB5 toxins
EA Merritt, WGJ Hol - Current opinion in structural biology, 1995 - Elsevier
Crystal structures of shiga and pertussis toxins have recently revealed a remarkable degree
of structural homology among the members of the AB5 class of bacterial toxins. Other …
of structural homology among the members of the AB5 class of bacterial toxins. Other …
Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori–infected adults
P Michetti, C Kreiss, KL Kotloff, N Porta, JL Blanco… - Gastroenterology, 1999 - Elsevier
Background & Aims: Oral immunization with Helicobacter pylori urease can cure
Helicobacter infection in animals. As a step toward therapeutic immunization in humans, the …
Helicobacter infection in animals. As a step toward therapeutic immunization in humans, the …
[HTML][HTML] Characterization and application of a new optical probe for membrane lipid domains
L Jin, AC Millard, JP Wuskell, X Dong, D Wu, HA Clark… - Biophysical journal, 2006 - cell.com
In this article, we characterize the fluorescence of an environmentally sensitive probe for
lipid membranes, di-4-ANEPPDHQ. In large unilamellar lipid vesicles (LUVs), its emission …
lipid membranes, di-4-ANEPPDHQ. In large unilamellar lipid vesicles (LUVs), its emission …