Intranasal repaglinide-solid lipid nanoparticles integrated in situ gel outperform conventional oral route in hypoglycemic activity

SM Elkarray, RM Farid, MM Abd-Alhaseeb… - Journal of Drug Delivery …, 2022 - Elsevier
Repaglinide (REP) loaded solid-lipid nanoparticles (SLNs) for intranasal administration is
the subject of the current work aiming enhancement of diabetes pharmacotherapy. SLNs …

[PDF][PDF] Impact of hydrophilic polymer solubilization on bioavailability enhancement of repaglinide by solid dispersion

M El-Nabarawi, I Khalil, R Saad - Inven Rapid Pharm Tech, 2016 - researchgate.net
Repaglinide (RPG) is poorly water soluble drug BCS (Low solubility, High permeability). The
objective of this study was to enhance the dissolution of RPG for oral drug delivery. RPG …

Hexyl alginate derivative, an amphiphilic innovative buccal film-forming material of promising mechanical and release characteristics for the improvement of …

A Khames - Drug Design, Development and Therapy, 2019 - Taylor & Francis
Background Association of long hydrocarbon chain with alginate molecule imparts surface
active properties and increases chain flexibility. Purpose This work studied the efficacy of …

Enhancement of Repaglinide Dissolving Rate by the Application of the Solid Dispersion Method

M Patel, A Indurkhya, G Saraogi, MA Khan - International Journal of …, 2024 - ijnrph.com
The recent work primarily set out to evaluate and synthesize the Repaglinide (RG) solid
dispersion. The medicine rifampicin is classified as a class II biopharmaceutical due to its …

In-vitro evaluation of binary and ternary carbamazepine solid dispersion

S Akhter, AKMS Uddin, M Salahuddin… - … Australasian Journal of …, 2016 - banglajol.info
The purpose of this research work was to improve the aqueous solubility and dissolution
rate of carbamzepine by solid dispersion (SD) technique. Polyethylene Glycol 6000 …

Improvement of Dissolution Rate of Repaglinide by Utilizing Solid Dispersion Technique

M Patel, A Indurkhya, MA Khan - Current Research in …, 2023 - crpsonline.com
The recent study's objective was to prepare and evaluate the Repaglinide (RG) solid
dispersion. RG is poorly water soluble, BCS class II drug. Repaglinide solid dispersion (RG …

FORMULATION AND EVALUATION OF BILAYER FLOATING TABLETS FOR THE TREATMENT OF DIABETES MELLITUS

B Kumar, M Kalim, S Yadav, PK Katiyar - NeuroQuantology, 2022 - search.proquest.com
Diabetes is a chronic disorder. It may be characterized by hyperglycaemia. These may help
ininsulin secretion defects and both insulin action. Due to development of insulin resistance …

[PDF][PDF] FORMULATION AND EVALUATION OF α-TOCOPHEROL ACETATE TABLET BY LIQUID-SOLID TECHNOLOGY

AK Sachan, V Kumar, S Kumar, K Kumari… - INTERNATIONAL …, 2019 - researchgate.net
The objective of this research was to develop a liquisolid (LS) formulation of dl-α tocopherol
acetate with improved dissolution properties and evaluate its strength to excipient …

[PDF][PDF] Mohammad Fahim Kadir2 1Department of Pharmacy, BGC Trust University Bangladesh, Chittagong-4000, Bangladesh 2Department of Pharmacy, University of …

S Akhter, AKMS Uddin, M Salahuddin, MW Mia… - academia.edu
The purpose of this research work was to improve the aqueous solubility and dissolution
rate of carbamzepine by solid dispersion (SD) technique. Polyethylene Glycol 6000 …

[引用][C] 瑞格列奈固体分散体的制备及体外溶出

李建伟, 海丽娜, 申爱卓, 宋素丽 - 沈阳药科大学学报, 2014