Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Tetracyclines possess many properties considered ideal for antibiotic drugs, including
activity against Gram-positive and-negative pathogens, proven clinical safety, acceptable …

Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Gram-negative bacteria express a plethora of efflux pumps that are capable of transporting
structurally varied molecules, including antibiotics, out of the bacterial cell. This efflux lowers …

Pathogenic Acinetobacter species, most notably Acinetobacter baumannii, are a significant
cause of healthcare‐associated infections worldwide. Acinetobacter infections are of …

Gram-negative pathogens such as Klebsiella pneumoniae, Acinetobacter baumannii, and
Pseudomonas aeruginosa are the leading cause of nosocomial infections throughout the …

Tigecycline is unique glycylcycline class of semisynthetic antimicrobial agents developed for
the treatment of polymicrobial infections caused by multidrug-resistant Gram-positive and …

Nosocomial infections with Acinetobacter baumannii are a global problem in intensive care
units with high mortality rates. Increasing resistance to first-and second-line antibiotics has …

We investigated the mechanisms of resistance to carbapenems, aminoglycosides,
glycylcyclines, tetracyclines, and quinolones in 90 multiresistant clinical strains of …