Human coronaviruses: a review of virus–host interactions

YX Lim, YL Ng, JP Tam, DX Liu - Diseases, 2016 - mdpi.com
Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …

The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
Abstract The coronavirus disease (COVID-19) has once again reminded us of the
significance of host immune response and consequential havocs of the immune …

Peptide SMIM30 promotes HCC development by inducing SRC/YES1 membrane anchoring and MAPK pathway activation

Y Pang, Z Liu, H Han, B Wang, W Li, C Mao, S Liu - Journal of hepatology, 2020 - Elsevier
Background & Aims Growing evidence shows that some non-coding RNAs (ncRNAs)
contain small open reading frames (smORFs) that are translated into short peptides. Herein …

[HTML][HTML] Hepatitis B virus molecular biology and pathogenesis

RJ Lamontagne, S Bagga, MJ Bouchard - Hepatoma research, 2016 - ncbi.nlm.nih.gov
As obligate intracellular parasites, viruses need a host cell to provide a milieu favorable to
viral replication. Consequently, viruses often adopt mechanisms to subvert host cellular …

Molecular mechanisms of hepatocellular carcinoma

RN Aravalli, CJ Steer, ENK Cressman - Hepatology, 2008 - journals.lww.com
Hepatocellular carcinoma (HCC) typically has poor prognosis, because it is often diagnosed
at an advanced stage. Heterogeneous phenotypic and genetic traits of affected individuals …

Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants

Z Gao, D Zhang, X Wang, X Zhang, Z Wen… - Nature …, 2022 - nature.com
Mitogen-activated protein kinase (MAPK) cascades play an important role in innate immunity
against various pathogens in plants and animals. However, we know very little about the …

Human DNA virus exploitation of the MAPK-ERK cascade

JK DuShane, MS Maginnis - International journal of molecular sciences, 2019 - mdpi.com
The extracellular signal-regulated kinases (ERKs) comprise a particular branch of the
mitogen-activated protein kinase cascades (MAPK) that transmits extracellular signals into …

[PDF][PDF] Host factors and failure of interferon‐α treatment in hepatitis C virus

B Gao, F Hong, S Radaeva - Hepatology, 2004 - Wiley Online Library
Failure of interferon‐α (IFN‐α) treatment in patients with chronic hepatitis C virus (HCV)
infection is a challenging obstacle for clinical and experimental hepatology. Both viral and …

FAM83D activates the MEK/ERK signaling pathway and promotes cell proliferation in hepatocellular carcinoma

D Wang, S Han, R Peng, X Wang, XX Yang… - Biochemical and …, 2015 - Elsevier
Publicly available microarray data suggests that the expression of FAM83D (Family with
sequence similarity 83, member D) is elevated in a wide variety of tumor types, including …

Epstein–Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitro

JD O'Neil, TJ Owen, VHJ Wood… - Journal of General …, 2008 - microbiologyresearch.org
The Epstein–Barr virus (EBV)-encoded EBNA1 protein is expressed in all virus-associated
tumours, including nasopharyngeal carcinoma (NPC), where it plays an essential role in …