Although stress and adversity are largely universal experiences, people exposed to greater
hardship are at increased risk for negative health consequences. Recent studies identify …

As global interest in the therapeutic potential of cannabis and its' derivatives for the
management of selected diseases increases, it is increasingly imperative that the toxic …

Prenatal cannabis exposure (PCE) is associated with mental health problems in early
adolescence, but the possible neurobiological mechanisms remain unknown. In a large …

Tobacco, alcohol, and marijuana consumption is an important public health problem
because of their high use worldwide and their association with the risk of mortality and many …

Recent European data facilitate an epidemiological investigation of the controversial
cannabis–cancer relationship. Of particular concern were prior findings associating high …

Earlier pubertal timing is associated with accelerated epigenetic aging, but the underlying
mechanisms are not well understood. This three-wave longitudinal study examined negative …

Objective To test whether childhood mental health symptoms, substance use, and early
adversity accelerate the rate of DNA methylation (DNAm) aging from adolescence to …

Background Cannabis is often characterised as a young person's drug. However, people
who began consuming cannabis in the 1970s and 1980s are no longer young and some …

Much recent attention has been directed toward the spatial organization of the cell nucleus
and the manner in which three-dimensional topologically associated domains and …

While classical laboratory and animal data have long established cannabinoid genotoxicity,
it is only recently, with the application of modern analytical techniques, that the scale of …