[HTML][HTML] Acute ischemic stroke in the clinic and the laboratory Targets for translational research

B Franx, RM Dijkhuizen, DWJ Dippel - Neuroscience, 2024 - Elsevier
Ischemic stroke research has enabled significant advancements in diagnosis, treatment, and
management of this debilitating disease, yet challenges remain standing in the way of better …

Propofol anesthesia improves stroke outcomes over isoflurane anesthesia—a longitudinal multiparametric MRI study in a rodent model of transient middle cerebral …

BAA Franx, GAF van Tilborg, A van der Toorn… - Frontiers in …, 2024 - frontiersin.org
General anesthesia is routinely used in endovascular thrombectomy procedures, for which
volatile gas and/or intravenous propofol are recommended. Emerging evidence suggests …

Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats–Comparison between ultrafast ultrasound and dynamic susceptibility …

BAA Franx, F Lebrun, L Chin Joe Kie… - Journal of Cerebral …, 2024 - journals.sagepub.com
Tomographic perfusion imaging techniques are integral to translational stroke research
paradigms that advance our understanding of the disease. Functional ultrasound (fUS) is an …

Chronic hypertension and perfusion deficits conjointly affect disease outcome after tPA treatment in a rodent model of thromboembolic stroke

BAA Franx, IACW Tiebosch, A van der Toorn… - bioRxiv, 2024 - biorxiv.org
Futile recanalization hampers prognoses for ischemic stroke patients despite successful
recanalization therapy. Allegedly, hypertension and reperfusion deficits contribute, but a …