Carbohydrate polymer-based nanocomposites for breast cancer treatment

FD Moghaddam, G Heidari, EN Zare, E Djatoubai… - Carbohydrate …, 2023 - Elsevier
Breast cancer is known as the most common invasive malignancy in women with the highest
mortality rate worldwide. This concerning disease may be presented in situ (relatively easier …

[HTML][HTML] Encapsulation: a strategy to deliver therapeutics and bioactive compounds?

I Klojdová, T Milota, J Smetanová, C Stathopoulos - Pharmaceuticals, 2023 - mdpi.com
There is a growing demand for efficient medical therapies without undesired side effects that
limit their application. Targeted therapies such as deliveries of pharmacologically active …

[HTML][HTML] The Power of Field-Flow Fractionation in Characterization of Nanoparticles in Drug Delivery

J Bian, N Gobalasingham, A Purchel, J Lin - Molecules, 2023 - mdpi.com
Asymmetric-flow field-flow fractionation (AF4) is a gentle, flexible, and powerful separation
technique that is widely utilized for fractionating nanometer-sized analytes, which extend to …

Materials and structure of polysaccharide-based delivery carriers for oral insulin: A review

X Wang, H Sun, T Mu - Carbohydrate Polymers, 2023 - Elsevier
Diabetes mellitus is a chronic metabolic disease that affects> 500 million patients worldwide.
Subcutaneous injection of insulin is the most effective treatment at present. However, regular …

[HTML][HTML] Removing the sporoderm from the sporoderm-broken spores of Ganoderma lucidum improves the anticancer and immune-regulatory activity of the water …

L Fang, Q Zhao, C Guo, D Guo, Z Li, J Xu, C Guo… - Frontiers in …, 2022 - frontiersin.org
Plant-derived polysaccharides have demonstrated promising anti-cancer effects via immune-
regulatory activity. The aim of the current study was to compare the chemical property and …

[HTML][HTML] Investigations of electronic, structural, and in silico anticancer potential of persuasive phytoestrogenic isoflavene-based Mannich bases

S Mutahir, MA Khan, M Mushtaq, H Deng, AM Naglah… - Molecules, 2023 - mdpi.com
Isoflavenes have received the greatest research attention among the many groups of
phytoestrogens. In this study, various isoflavene-based Mannich bases were selected for …

[HTML][HTML] A Small Sugar Molecule with Huge Potential in Targeted Cancer Therapy

G Pastuch-Gawołek, J Szreder, M Domińska, M Pielok… - Pharmaceutics, 2023 - mdpi.com
The number of cancer-related diseases is still growing. Despite the availability of a large
number of anticancer drugs, the ideal drug is still being sought that would be effective …

[HTML][HTML] Biopolymeric prodrug systems as potential antineoplastic therapy

AA Chis, AM Arseniu, C Morgovan, CM Dobrea, A Frum… - Pharmaceutics, 2022 - mdpi.com
Nowadays, cancer represents a major public health issue, a substantial economic issue,
and a burden for society. Limited by numerous disadvantages, conventional chemotherapy …

Hyaluronic acid/dextran-based polymeric micelles co-delivering ursolic acid and doxorubicin to mitochondria for potentiating chemotherapy in MDR cancer

Y Guo, X Yang, Y Zhang, F Luo, J Yang, X Zhang… - Carbohydrate …, 2024 - Elsevier
Cancer multidrug resistance (MDR) dramatically hindered the efficiency of standard
chemotherapy. Mitochondria are highly involved in the occurrence and development of …

[HTML][HTML] Selenium nanoparticles coated bacterial polysaccharide with potent antimicrobial and anti-lung cancer activities

NS Shehata, BH Elwakil, SS Elshewemi… - Scientific Reports, 2023 - nature.com
Bacterial exopolysaccharides are homopolymeric or heteropolymeric polysaccharides with
large molecular weights (10–1000 kDa). Exopolysaccharides' functional uses and potential …