Are the Organoid Models an Invaluable Contribution to ZIKA Virus Research?

P Marrazzo, M Cricca, C Nastasi - Pathogens, 2021 - mdpi.com
In order to prevent new pathogen outbreaks and avoid possible new global health threats, it
is important to study the mechanisms of microbial pathogenesis, screen new antiviral agents …

Immune profile of the normal maternal-fetal interface in rhesus macaques and its alteration following zika virus infection

MJ Moström, EA Scheef, LM Sprehe… - Frontiers in …, 2021 - frontiersin.org
The maternal decidua is an immunologically complex environment that balances
maintenance of immune tolerance to fetal paternal antigens with protection of the fetus …

Transcriptional signatures of Zika virus infection in astrocytes

B Schouest, TA Peterson, DM Szeltner… - Journal of …, 2021 - Springer
Astrocytes are an early and important target of Zika virus (ZIKV) infection in the developing
brain, but the impacts of infection on astrocyte function remain controversial. Given that …

Molecular Approaches for the Validation of the Baboon as a Nonhuman Primate Model for the Study of Zika Virus Infection

E Mask, VL Hodara, JE Callery, LM Parodi… - Frontiers in Cellular …, 2022 - frontiersin.org
Nonhuman primates (NHP) are particularly important for modeling infections with viruses
that do not naturally replicate in rodent cells. Zika virus (ZIKV) has been responsible for …