Abstract Context Prostate cancer (PCa) is one of the most common cancers worldwide.
Understanding the epidemiology and risk factors of the disease is paramount to improve …

Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

Selenium is an essential microelement required for a number of biological functions.
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 …

Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …

Our understanding of nonalcoholic fatty liver disease pathophysiology continues to advance
rapidly. Accordingly, the field has moved from describing the clinical phenotype through the …

This review addresses the role of the essential trace element, selenium, in type-2 diabetes
mellitus (T2DM) and its metabolic co-morbidities, ie, metabolic syndrome, obesity and non …

Importance Cardiovascular disease and cancer are the 2 leading causes of death in the US,
and vitamin and mineral supplementation has been proposed to help prevent these …

Reactive oxygen species (ROS) play important roles in tissue homeostasis, cellular
signaling, differentiation, and survival. In this review, we discuss the types of ROS, their …

There is evidence that diet and nutrition are modifiable risk factors for several cancers, but
associations may be flawed due to inherent biases. Nutritional epidemiology studies have …

Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …