Tumor growth creates a hypoxic microenvironment, which promotes angiogenesis and
aggressive tumor growth and invasion. HIF1α is a central molecule involved in mediating …

Hypoxia‐inducible factors (HIFs) belong to a family of transcription factors (TF) responsive to
a low O2 availability, which is often a characteristic feature of solid tumors. The alpha …

Introduction: Oral lichen planus (OLP) is a T-cell-mediated chronic inflammatory
autoimmune disease affecting 0.1% to 4% of the world population. The WHO has already …

This study attempts to evaluate the prognostic role of PHYH for overall survival (OS) in clear
cell renal cell carcinoma (ccRCC) by means of publicly available data from The Cancer …

The hypoxia-inducible factor (HIF) family of transcription factors plays central roles in the
development, physiology, pathology, and environmental adaptation of animals. Because …

Aim: To investigate hypoxia inducible factor-1α's (HIF-1α) immunohistochemical expression
in clear cell renal cell carcinoma (ccRCC) treated with radical nephrectomy. Patients and …

Abstract Hypoxia-inducible factor-1 (HIF-1), an important component of angiogenesis, is
activated as a response to tumor hypoxia and facilitates tumor survival. Several case–control …

Background: Hypoxia inducible factor-1 alpha (HIF-$1 {\alpha} $) is the key regulator of
cellular responses to hypoxia and plays a central role in tumour growth. Presence of Single …

Objective This meta-analysis was implemented to evaluate the association between hypoxia-
inducible factor-1α (HIF-1α) C1772T/G1790A polymorphisms and susceptibility to head and …

β-ARs are extensively spread in different tissues of our body, which could be activated by
neurotransmitters norepinephrine and epinephrine to mediate physiological function and …