Uveal melanoma: relatively rare but deadly cancer

S Kaliki, CL Shields - Eye, 2017 - nature.com
Although it is a relatively rare disease, primarily found in the Caucasian population, uveal
melanoma is the most common primary intraocular tumor in adults with a mean age …

[HTML][HTML] Metastatic uveal melanoma: The final frontier

ES Rantala, MM Hernberg, S Piperno-Neumann… - Progress in Retinal and …, 2022 - Elsevier
Abstract Treatment of primary intraocular uveal melanoma has developed considerably, its
driver genes are largely unraveled, and the ways to assess its risk for metastases are very …

Uveal melanoma: epidemiology, etiology, and treatment of primary disease

BA Krantz, N Dave, KM Komatsubara… - Clinical …, 2017 - Taylor & Francis
Uveal melanoma (UM) is the most common intraocular malignancy and arises from
melanocytes in the iris, ciliary body, or choroid. Early diagnosis and local treatment is …

Uveal melanoma: 5-year update on incidence, treatment, and survival (SEER 1973-2013)

ME Aronow, AK Topham, AD Singh - Ocular oncology and pathology, 2018 - karger.com
Purpose: To analyze trends in incidence, treatment, and survival of uveal melanoma in the
United States from 1973 to 2013 using the Surveillance, Epidemiology, and End Results …

Uveal melanoma: trends in incidence, treatment, and survival

AD Singh, ME Turell, AK Topham - Ophthalmology, 2011 - Elsevier
PURPOSE: To determine trends in incidence, treatment, and survival with primary uveal
melanoma in the United States over a 36-year period from 1973 to 2008. DESIGN …

Effect of selumetinib vs chemotherapy on progression-free survival in uveal melanoma: a randomized clinical trial

RD Carvajal, JA Sosman, JF Quevedo, MM Milhem… - Jama, 2014 - jamanetwork.com
Importance Uveal melanoma is characterized by mutations inGNAQandGNA11, resulting in
mitogen-activated protein kinase pathway activation. Objective To assess the efficacy of …

The biology of uveal melanoma

A Amaro, R Gangemi, F Piaggio, G Angelini… - Cancer and Metastasis …, 2017 - Springer
Uveal melanoma (UM), a rare cancer of the eye, is distinct from cutaneous melanoma by its
etiology, the mutation frequency and profile, and its clinical behavior including resistance to …

Current molecular and clinical insights into uveal melanoma

M Fallico, G Raciti, A Longo… - International …, 2021 - spandidos-publications.com
Uveal melanoma (UM) represents the most prominent primary eye cancer in adults. With an
incidence of approximately 5 cases per million individuals annually in the United States, UM …

Incidence of noncutaneous melanomas in the US

CC McLaughlin, XC Wu, A Jemal… - … Journal of the …, 2005 - Wiley Online Library
BACKGROUND Description of the epidemiology of noncutaneous melanoma has been
hampered by its rarity. The current report was the largest in‐depth descriptive analysis of …

Clinical spectrum and prognosis of uveal melanoma based on age at presentation in 8,033 cases

CL Shields, S Kaliki, M Furuta, A Mashayekhi… - Retina, 2012 - journals.lww.com
Purpose: To evaluate clinical features and life prognosis of uveal melanoma based on age
at presentation. Design: Retrospective, nonrandomized, interventional case series. Results …