Sensing and regulation of reactive sulfur species (RSS) in bacteria
DP Giedroc, GT Antelo, JN Fakhoury… - Current Opinion in …, 2023 - Elsevier
The infected host deploys generalized oxidative stress caused by small inorganic reactive
molecules as antibacterial weapons. An emerging consensus is that hydrogen sulfide (H 2 …
molecules as antibacterial weapons. An emerging consensus is that hydrogen sulfide (H 2 …
Carbon monoxide-sensing transcription factors: regulators of microbial carbon monoxide oxidation pathway gene expression
Carbon monoxide (CO) serves as a source of energy and carbon for a diverse set of
microbes found in anaerobic and aerobic environments. The enzymes that bacteria and …
microbes found in anaerobic and aerobic environments. The enzymes that bacteria and …
Polysulfide metabolizing enzymes influence SqrR-mediated sulfide-induced transcription by impacting intracellular polysulfide dynamics
T Shimizu, T Ida, GT Antelo, Y Ihara, JN Fakhoury… - PNAS …, 2023 - academic.oup.com
Sulfide plays essential roles in controlling various physiological activities in almost all
organisms. Although recent evidence has demonstrated that sulfide is endogenously …
organisms. Although recent evidence has demonstrated that sulfide is endogenously …
Bacterial Metallostasis: Metal Sensing, Metalloproteome Remodeling, and Metal Trafficking
DA Capdevila, JJ Rondón, KA Edmonds… - Chemical …, 2024 - ACS Publications
Transition metals function as structural and catalytic cofactors for a large diversity of proteins
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …
Sulfane sulfur posttranslationally modifies the global regulator AdpA to influence actinorhodin production and morphological differentiation of Streptomyces coelicolor
T Lu, X Wu, Q Cao, Y Xia, L Xun, H Liu - Mbio, 2022 - Am Soc Microbiol
The transcription factor AdpA is a key regulator controlling both secondary metabolism and
morphological differentiation in Streptomyces. Due to its critical functions, its expression …
morphological differentiation in Streptomyces. Due to its critical functions, its expression …
Possible molecular basis of the biochemical effects of cysteine-derived persulfides
E Cuevasanta, D Benchoam, JA Semelak… - Frontiers in Molecular …, 2022 - frontiersin.org
Persulfides (RSSH/RSS−) are species closely related to thiols (RSH/RS−) and hydrogen
sulfide (H2S/HS−), and can be formed in biological systems in both low and high molecular …
sulfide (H2S/HS−), and can be formed in biological systems in both low and high molecular …
Methods in sulfide and persulfide research
Sulfides and persulfides/polysulfides (RS n-Rʹ, n> 2; RS nH, n> 1) are endogenously
produced metabolites that are abundant in mammalian and human cells and tissues. The …
produced metabolites that are abundant in mammalian and human cells and tissues. The …
Increased intracellular H2S levels enhance iron uptake in Escherichia coli
S Nonoyama, S Maeno, Y Gotoh, R Sugimoto… - Mbio, 2024 - journals.asm.org
We investigated the impact of intracellular hydrogen sulfide (H2S) hyperaccumulation on the
transcriptome of Escherichia coli. The wild-type (WT) strain overexpressing mstA, encoding …
transcriptome of Escherichia coli. The wild-type (WT) strain overexpressing mstA, encoding …
In the Alphaproteobacterium Hyphomicrobium denitrificans SoxR Serves a Sulfane Sulfur-Responsive Repressor of Sulfur Oxidation
In organisms that use reduced sulfur compounds as alternative or additional electron donors
to organic compounds, transcriptional regulation of genes for enzymes involved in sulfur …
to organic compounds, transcriptional regulation of genes for enzymes involved in sulfur …
The Sulfide-Responsive SqrR/BigR Homologous Regulator YgaV of Escherichia coli Controls Expression of Anaerobic Respiratory Genes and Antibiotic Tolerance
R Balasubramanian, K Hori, T Shimizu, S Kasamatsu… - Antioxidants, 2022 - mdpi.com
Compositions and activities of bacterial flora in the gastrointestinal tract significantly
influence the metabolism, health, and disease of host humans and animals. These enteric …
influence the metabolism, health, and disease of host humans and animals. These enteric …