The number of chemicals for which environmental regulatory decisions are required far
exceeds the current capacity for toxicity testing. High-throughput screening commonly used …

Abstract The Toxicology Forum convened an international state-of-the-science workshop
Assessing Chemical Carcinogenicity: Hazard Identification, Classification, and Risk …

Point-of-care technology is a term used to describe any treatment given at the “site-of-need”.
The span of point-of-care has broadened, growing from its current dominant usage in clinical …

Abstract The European Partnership for Alternative Approaches to Animal Testing (EPAA)
convened a Partners' Forum Toxicokinetics and Read-Across to provide an overview on …

Top dose selection for repeated dose animal studies has generally focused on identification
of apical endpoints, use of the limit dose, or determination of a maximum tolerated dose …

For the purposes of chemical safety assessment, the value of using non-animal (in silico and
in vitro) approaches and generating mechanistic information on toxic effects is being …

Crop protection active ingredients and formulated products are essential tools for modern
agriculture that serve to prevent yield loss related to insect, weed, or fungal pest pressure …

Human health risk assessment is historically built upon animal testing, often following
Organisation for Economic Co-operation and Development (OECD) test guidelines and …

The KMD (kinetically-derived maximum dose) is an increasingly advocated concept that
uses toxicokinetic data in the top dose selection for toxicity testing. Application of this …

Human biomonitoring (HBM) as a tool for occupational exposure assessment has been
reviewed, with a specific focus on pesticides. A systematic literature review (SLR) of …