Advanced technologies for the development of infectious disease vaccines
Vaccines play a critical role in the prevention of life-threatening infectious disease. However,
the development of effective vaccines against many immune-evading pathogens such as …
the development of effective vaccines against many immune-evading pathogens such as …
Pathogenesis and virulence of coronavirus disease: Comparative pathology of animal models for COVID-19
Animal models that can replicate clinical and pathologic features of severe human
coronavirus infections have been instrumental in the development of novel vaccines and …
coronavirus infections have been instrumental in the development of novel vaccines and …
Safety, immunogenicity and efficacy of an mRNA-based COVID-19 vaccine, GLB-COV2-043, in preclinical animal models
F Lelis, LA Byk, S Pustylnikov, V Nguyen, B Nguyen… - Scientific Reports, 2023 - nature.com
Several COVID-19 vaccines, some more efficacious than others, are now available and
deployed, including multiple mRNA-and viral vector-based vaccines. With the focus on …
deployed, including multiple mRNA-and viral vector-based vaccines. With the focus on …
Bivalent mRNA vaccine effectiveness against SARS-CoV-2 variants of concern
M Kumari, SC Su, KH Liang, HT Lin, YF Lu… - Journal of Biomedical …, 2023 - Springer
Background Sequential infections with SARS-CoV-2 variants such as Alpha, Delta, Omicron
and its sublineages may cause high morbidity, so it is necessary to develop vaccines that …
and its sublineages may cause high morbidity, so it is necessary to develop vaccines that …
[HTML][HTML] Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates
Immunization with mRNA or viral vectors encoding spike with diproline substitutions (S-2P)
has provided protective immunity against severe COVID-19 disease. How immunization with …
has provided protective immunity against severe COVID-19 disease. How immunization with …
Enhancing RNA Payload and Temperature Stability and Activity with Cationic Peptide-Coated Zinc Oxide Nanoparticles
The lipid nanoparticle (LNP) mRNA vaccine was first tested through clinic but suffered from
relatively low RNA payloads and poor temperature stability. Our lab patented a protamine …
relatively low RNA payloads and poor temperature stability. Our lab patented a protamine …
Role of gamma irradiation and disaccharide trehalose to induce immune responses in Syrian hamster model against Iranian SARS-CoV-2 virus isolate
F Motamedi Sedeh, A Khorasani, M Lotfi… - Veterinary Research …, 2024 - vrf.iranjournals.ir
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is the causative
agent of the emerging zoonotic respiratory disease. One of the most important prerequisites …
agent of the emerging zoonotic respiratory disease. One of the most important prerequisites …
[HTML][HTML] A Review of COVID-19 Vaccines, Immunogenicity, Safety, and Efficacy toward Addressing Vaccine Hesitancy, Inequity, and Future Epidemic Preparedness
S Puth, V Loeurng - Epidemic Preparedness and Control, 2023 - intechopen.com
This chapter provides an update on COVID-19 vaccines, emphasizing their immunogenicity,
safety, efficacy, and potential impact on vaccine hesitancy, inequity, and future epidemic …
safety, efficacy, and potential impact on vaccine hesitancy, inequity, and future epidemic …
Immune Responses Following Administration of Whole Gamma Irradiated SARS-CoV-2 Vaccine Stabilized With Disaccharide Trehalose on Syrian Hamster Model
F Motamedi-Sedeh, A Khorasani, M Lotfi, SM Moosavi… - 2023 - researchsquare.com
Background The SARS-CoV-2 virus is the causative agent of the emerging respiratory
zoonosis disease. One of the most important requirements for the control of emerging …
zoonosis disease. One of the most important requirements for the control of emerging …
[PDF][PDF] Improved vaccination strategies against emerging zoonotic coronaviruses using MVA vector technology
C Meyer zu Natrup - 2023 - elib.tiho-hannover.de
TCR T cell receptor Tfh T follicular helper cell Th T helper cell Th1 T helper cell 1 Th17 T
helper cell 17 Th2 T helper cell 2 TNFα Tumor necrosis factor alpha TRS Transcription …
helper cell 17 Th2 T helper cell 2 TNFα Tumor necrosis factor alpha TRS Transcription …