Background Millions of tourists and climbers visit high altitudes annually. Many
unsuspecting and otherwise healthy individuals may get sick when sojourning to these high …

Objectives To assess the efficacy of three different daily doses of acetazolamide in the
prevention of acute mountain sickness and to determine the lowest effective dose. Design …

Background High altitude illness (HAI) is a term used to describe a group of cerebral and
pulmonary syndromes that can occur during travel to elevations above 2500 metres (8200 …

Background Acute high altitude illness is defined as a group of cerebral and pulmonary
syndromes that can occur during travel to high altitudes. It is more common above 2500 …

Abstract Kayser, Bengt, Lionel Dumont, Christopher Lysakowski, Christophe Combescure,
Guy Haller, Martin R. Tramèr. Reappraisal of acetazolamide for the prevention of acute …

Background Acetazolamide has been reported to be effective in the prevention of acute
mountain sickness (AMS). Our aim was to conduct a systematic review of randomized …

Reactive oxygen species (ROS) formed during acute high altitude exposure contribute to
cerebral vascular leak and development of acute mountain sickness (AMS). Nuclear factor …

Introduction: The physiological responses on exposure to high altitude are relatively well
known, but new discoveries are still being made, and novel prevention and treatment …

Introduction North American guidelines propose 125 mg acetazolamide twice daily as the
recommended prophylactic dose to prevent acute mountain sickness (AMS). To our …

Extravehicular activity (EVA) is at the core of a manned space exploration program. There
are elements of exploration that may be safely and effectively performed by robots, but there …