Prevalence studies of challenging behaviors among children with disabilities have a
potential value, as they provide information for intervention and evaluation. However, the …

Objective The behavioral phenotype of neurogenetic disorders associated with intellectual
disability often includes psychiatric comorbidity. The objectives of this systematic review and …

With an incidence of~ 1 in 800 births, Down syndrome (DS) is the most common
chromosomal condition linked to intellectual disability worldwide. While the genetic basis of …

Abstract Behavioural and Psychological Symptoms of Dementia (BPSD) are a core symptom
of dementia and are associated with suffering, earlier institutionalization and accelerated …

Background Numerous studies have proven the significant positive impact of the regular
physical activity on general health conditions and quality of life of people with intellectual …

Volunteer activities can provide opportunities to learn new skills, build social networks, and
contribute to enhanced self-esteem. Volunteering also provides a positive contribution to …

Aberrant neurodevelopment in Down syndrome (DS)—caused by triplication of human
chromosome 21—is commonly attributed to gene dosage imbalance, linking overexpression …

Down syndrome (DS) is caused by three copies of human chromosome 21 (Hsa21) and
results in phenotypes including intellectual disability and skeletal deficits. Ts65Dn mice have …

Objective: There are many challenges to health, functioning, and participation for children
with Down syndrome; yet, the quality-of-life (QOL) domains important for this group have …

Adolescents with Down syndrome can demonstrate increased behavior problems as
compared with typical peers. Few studies have explored whether behavior impacts adaptive …