Matrix Metalloproteinases: A challenging paradigm of cancer management

A Alaseem, K Alhazzani, P Dondapati, S Alobid… - Seminars in cancer …, 2019 - Elsevier
Matrix metalloproteinases (MMPs) are members of zinc-dependent endopeptidases
implicated in a variety of physiological and pathological processes. Over the decades …

Collateral beauty in the damages: an overview of cosmetics and therapeutic applications of microbial proteases

SS Mousavi Ghahfarrokhi, FS Mahdigholi… - Archives of …, 2023 - Springer
Microbial proteases are enzymes secreted by a variety of microorganisms, including
bacteria and fungi, and have attracted significant attention due to their versatile applications …

Targeting glioblastoma multiforme using a novel fusion protein comprising interleukin-13 and staphylococcal enterotoxin B in vitro

Z Gholipour, AAI Fooladi, K Parivar, R Halabian - Toxicology in Vitro, 2023 - Elsevier
Targeting cell surface receptors with immunotoxins provides a novel, unique and highly
potent treatment against cancers. A high expression of interleukin-13 (IL13) receptor α2 …

A comparative study of the arazyme-based fusion proteins with various ligands for more effective targeting cancer therapy: an in-silico analysis

R Mehrab, H Sedighian… - Research in …, 2023 - journals.lww.com
Background and purpose: Recently, the use of immunotoxins for targeted cancer therapy
has been proposed, to find new anticancer drugs with high efficacy on tumor cells with …

Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1

N Nag, T Ray, R Tapader, A Gope, R Das, E Mahapatra… - Iscience, 2024 - cell.com
We have purified Peptidase M84 from Bacillus altitudinis in an effort to isolate anticancer
proteases from environmental microbial isolates. This metallo-protease had no discernible …

A limitless Brazilian scientist: Professor Travassos and his contribution to cancer biology

EG Rodrigues, AS Dobroff, DC Arruda, DB Tada… - Brazilian Journal of …, 2023 - Springer
Abstract Luiz Rodolpho Travassos, a Brazilian scientist recognized in several areas of
research, began his studies in the field of oncology in the late 1970s when he took a …

Cloning and expression of recombinant arazyme with anti-inflammatory and anti-breast cancer potential

Z Yahyaee, M Shahpari… - Archives of …, 2024 - Springer
Arazyme is an extracellular metalloprotease which is secreted by a Gram-negative symbiotic
bacterium called Serratia proteomaculans. There are limited studies on various biological …

Arazyme secreted by Serratia proteamaculans: current understanding in animal husbandry

DX Dang, WS Meng, SH Li, T Wang… - The Journal of Agricultural …, 2023 - cambridge.org
Arazyme, an alkaline metalloprotease, is produced by Serratia proteamaculans, a symbiotic
bacterium isolated from the intestinal ecosystem of Nephila clavata. Arazyme is known to …

Targeted therapies in HER2-positive breast cancer with receptor-redirected Arazyme-linker-Herceptin as a novel fusion protein

F Rahmani, H Ajoudanifar, N Arbab Soleimani… - Breast Cancer, 2024 - Springer
Background Targeted treatment of different types of cancers through highly expressed
cancer cell surface receptors by fusion proteins is an efficient method for cancer therapy …

[HTML][HTML] The anti-adhesion effect of nisin as a robust lantibiotic on the colorectal cancer cells

H Soleimanifar, HM Hosseini, SS Tehrani… - Advanced Biomedical …, 2023 - journals.lww.com
Background: Bacteriocins are a type of antimicrobial peptide that are produced by probiotics.
They have been studied as possible therapeutic drugs and have been used to suppress …