Abstract The 1, 4‐conjugated addition of nitrogen centered nucleophiles to electron‐
deficient alkenes is one of the most significant and widely used reactions in modern …

Cytisine is a quinolizidine alkaloid isolated from various Leguminosae plants. Cytisine and
its derivatives exhibit a broad range of biological properties, such as smoking cessation aid …

An earth-abundant and inexpensive Mn (I)-catalyzed alkylation of 2-pyridone with maleimide
has been reported for the first time, in contrast to previously reported Diels–Alder products …

N-Arylcytisine derivatives are quite rare. We report here a practical methodology to obtain
these compounds. Using the copper-catalyzed Chan-Lam coupling, we synthesized new N …

Abstract In this account, Diels-Alder reactions of different 1-amino-1, 3-dienes with
dienophiles are considered. As 1-amino-1, 3-dienes, dienamines, dienamides, 1, 2 …

Diels–Alder adducts of 12-N-substituted derivatives of (−)-cytisine with N-phenylmaleimide
were synthesized. The conditions of effective diastereodifferentiation were found: the …

For the first time, natural product Cytisine was successfully used as a reagent for thermal-
activated transannulation of 1H-tetrazoles and a series of cytisine-thienopyrimidinone …

Further development of the chemistry and applications of chiral compounds that possess
configurationally stable stereogenic nitrogen atoms is hampered by the lack of efficient …

The Diels–Alder reaction of N-benzylcytisine with N-methyl-and N-benzylmaleimides is
100% endo-selective and gives the corresponding syn-and anti-diastereomers in 11–42 …

The first direct synthesis of 3-N-methyl-9-formylcytisine via electrophylic formylation is
described. It is established, that Vilsmeier-Haack and Gatterman variants of this reaction are …