Emerging approaches to DNA data storage: challenges and prospects

A Doricchi, CM Platnich, A Gimpel, F Horn, M Earle… - ACS …, 2022 - ACS Publications
With the total amount of worldwide data skyrocketing, the global data storage demand is
predicted to grow to 1.75× 1014 GB by 2025. Traditional storage methods have difficulties …

Molecular digital data storage using DNA

L Ceze, J Nivala, K Strauss - Nature Reviews Genetics, 2019 - nature.com
Molecular data storage is an attractive alternative for dense and durable information storage,
which is sorely needed to deal with the growing gap between information production and the …

Synthetic DNA applications in information technology

LC Meiser, BH Nguyen, YJ Chen, J Nivala… - Nature …, 2022 - nature.com
Synthetic DNA is a growing alternative to electronic-based technologies in fields such as
data storage, product tagging, or signal processing. Its value lies in its characteristic …

DNA storage: research landscape and future prospects

Y Dong, F Sun, Z Ping, Q Ouyang… - National Science …, 2020 - academic.oup.com
The global demand for data storage is currently outpacing the world's storage capabilities.
DNA, the carrier of natural genetic information, offers a stable, resource-and energy-efficient …

A characterization of the DNA data storage channel

R Heckel, G Mikutis, RN Grass - Scientific reports, 2019 - nature.com
Owing to its longevity and enormous information density, DNA, the molecule encoding
biological information, has emerged as a promising archival storage medium. However, due …

Random access DNA memory using Boolean search in an archival file storage system

JL Banal, TR Shepherd, J Berleant, H Huang… - Nature materials, 2021 - nature.com
DNA is an ultrahigh-density storage medium that could meet exponentially growing
worldwide demand for archival data storage if DNA synthesis costs declined sufficiently and …

DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage

M Welzel, PM Schwarz, HF Löchel… - Nature …, 2023 - nature.com
The extensive information capacity of DNA, coupled with decreasing costs for DNA synthesis
and sequencing, makes DNA an attractive alternative to traditional data storage. The …

Terminator-free template-independent enzymatic DNA synthesis for digital information storage

HH Lee, R Kalhor, N Goela, J Bolot… - Nature communications, 2019 - nature.com
DNA is an emerging medium for digital data and its adoption can be accelerated by
synthesis processes specialized for storage applications. Here, we describe a de novo …

Data storage in DNA with fewer synthesis cycles using composite DNA letters

L Anavy, I Vaknin, O Atar, R Amit, Z Yakhini - Nature biotechnology, 2019 - nature.com
The density and long-term stability of DNA make it an appealing storage medium,
particularly for long-term data archiving. Existing DNA storage technologies involve the …

HEDGES error-correcting code for DNA storage corrects indels and allows sequence constraints

WH Press, JA Hawkins, SK Jones Jr… - Proceedings of the …, 2020 - National Acad Sciences
Synthetic DNA is rapidly emerging as a durable, high-density information storage platform. A
major challenge for DNA-based information encoding strategies is the high rate of errors that …