Delivery technologies for cancer immunotherapy

RS Riley, CH June, R Langer, MJ Mitchell - Nature reviews Drug …, 2019 - nature.com
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Gold nanoparticles-based photothermal therapy for breast cancer

MA Dheyab, AA Aziz, PM Khaniabadi… - Photodiagnosis and …, 2023 - Elsevier
AuNPs-mediated photothermal therapy (PTT) is gaining popularity in both laboratory
research and medical applications. It has proven clear advantages in breast cancer therapy …

Designed proteins assemble antibodies into modular nanocages

R Divine, HV Dang, G Ueda, JA Fallas, I Vulovic… - Science, 2021 - science.org
INTRODUCTION Antibodies that bind tightly to targets of interest play central roles in
biological research and medicine. Clusters of antibodies, typically generated by fusing …

m6A Reader YTHDF1‐Targeting Engineered Small Extracellular Vesicles for Gastric Cancer Therapy via Epigenetic and Immune Regulation

Q You, F Wang, R Du, J Pi, H Wang, Y Huo… - Advanced …, 2023 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) modulators decide the fate of m6A‐modified transcripts
and drive cancer development. RNA interference targeting m6A modulators promise to be …

Polymer micropatches as natural killer cell engagers for tumor therapy

S Prakash, N Kumbhojkar, A Lu, N Kapate, VC Suja… - ACS …, 2023 - ACS Publications
Natural killer (NK) cell therapies have emerged as a potential therapeutic approach to
various cancers. Their efficacy, however, is limited by their low persistence and anergy …

Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

Clinical applications of carbon nanomaterials in diagnostics and therapy

KP Loh, D Ho, GNC Chiu, DT Leong… - Advanced …, 2018 - Wiley Online Library
Nanomaterials have the potential to improve how patients are clinically treated and
diagnosed. While there are a number of nanomaterials that can be used toward improved …

Gold nanoparticles in virus detection: Recent advances and potential considerations for SARS‐CoV‐2 testing development

J Wang, AJ Drelich, CM Hopkins… - Wiley …, 2022 - Wiley Online Library
Viruses are infectious agents that pose significant threats to plants, animals, and humans.
The current coronavirus disease 2019 pandemic, which is caused by severe acute …

Artificial intelligence in nanomedicine

D Ho, P Wang, T Kee - Nanoscale Horizons, 2019 - pubs.rsc.org
The field of nanomedicine has made substantial strides in the areas of therapeutic and
diagnostic development. For example, nanoparticle-modified drug compounds and imaging …

Forming next-generation antibody–nanoparticle conjugates through the oriented installation of non-engineered antibody fragments

MK Greene, DA Richards, JCF Nogueira… - Chemical …, 2018 - pubs.rsc.org
The successful development of targeted nanotherapeutics is contingent upon the
conjugation of therapeutic nanoparticles to target-specific ligands, with particular emphasis …